Targeting infants now? Leave them alone!!!
Last week I came across a blog for pharmaceutical reps and employees, it was called Cafepharma and it allows people employed in the Pharmaceutical industry to post messages on a Message Board. Link
. I thought this was an interesting answer to a query posted by a prospective employee of lundbeck…
What’s it like to work for Lundbeck?
Please give me the good, bad, and the ugly. And pleeeeease…no snide remarks like CP posters often give. I’ve been approached to apply for a position (a product that is for intermittent seizures in infants). Anyone have any insight about the company and/or the product’s popularity/pros and cons of promoting it?
Thanks in advance to any serious posters.
Vigabatrin in the product. Serious side effects like making kids go blind. You better go speak with some child neuro`s in your area to get the real info. It is an end of the line product with very limited usage due to severe side effect risks. Be very careful with this company. If you`re asking for anonymous advice, I`d stay clear of it unless you just have been unemployed for a very long time and need a pay check.
The message board didn’t paint a pretty picture of lundbeck and subsequently I googled lundbeck’s product Vigabatrin, and sure enough it can cause irreversable blindness! It is an anti-epileptic drug that can be prescribed for intermittent seizures in infants. As far as I’m aware, you cant die from epilepsy so why would anyone prescribe this for an infant, when it’s possible that they can end up being blind as well as epileptic? Then if the child is old enough he/she might commit suicide or an act of agression, totally as a side-effect of the drug and the people that are left behind will never be informed of this! Surely there is a better alternative?
This is what it says on lundbeck’s own website… “Sabril causes permanent vision loss in infants, children and adults. The onset is unpredictable and can occur within weeks of starting treatment, or sooner, or at anytime during treatment even after months or years. Because of this risk of permanent vision loss, Sabril approval is accompanied by an FDA-mandated Risk Evaluation and Mitigation Strategy (REMS) and is available only through a special restricted distribution program called SHARE (Support Help and Resources for Epilepsy)”. Link
This drug Vigabatrin is marketed as Sabril® in America by Lundbeck Link and in Europe by Sanofi-Aventis. Link
Suicidal ideation and behaviour have also been reported in patients treated with anti-epileptic agents including this drug, along with congenital defects increasing 2 to 3 fold in children born from mothers treated with an antiepileptic; the most frequently reported are cleft lip, cardiovascular defects and neural tube defects.
Listed side effects are…
Common: agitation, aggression, nervousness, depression, paranoid reaction.
Uncommon: hypomania, mania, psychotic disorder
Rare: suicide attempt
Psychiatric reactions have been reported during vigabatrin therapy. These reactions occurred in patients with and without a psychiatric history and were usually reversible when vigabatrin doses were reduced or gradually discontinued.