Conflicting Information on both sides of the Atlantic.

Comparisons with consumer information for antidepressant medication here in Ireland and across the Atlantic, the U.S (FDA) and Health Canada…

In America antidepressants including Celexa/Cipramil have come with a black box warning since 2004 following studys which showed a greater risk of suicidality with patients treated with this medication.Link. The Black-box warning was updated in 2007 to include warnings for young adults up to age 24. Link.


FDA Warning… Antidepressant medicines may increase suicidal thoughts or actions in some children, teenagers, and young adults when the medicine is first started. Link.

Professor David Healy…”while extraordinarily rare, SSRI’s could spark suicidal or homicidal reactions”.

Irish College of Psychiatry…The training body for psychiatrists in this country has said that there is ‘no evidence’ of a link existing between antidepressant use and homicide, and that research has failed to establish a causal link between the use of these medications and suicide…Link.

Scientific Evidence…

1: ‘Antidepressants and Violence; Prof. David Healy et al. PLoS Medicine, here.

2. ‘Suicidality, Violence and Mania Caused by SSRIs; Dr Peter R Breggin. here.

3. PLoS one..drugs associated with violence. Here.


Celexa/Cipramil, Patient Information Leaflet FDA. Link.  The same drug with a much lesser warning… Cipramil PIL Ireland.

FDA, Celexa Alert for Celexa in pregnancy. Link. IMB…None.


The manufacturers of Celexa/Cipramil Lundbeck (Forest Labs have the licence to kill, sorry I meant sell, in the U.S) also have conflicting opinions, depending on which country you live in…


Ireland. A statement from Lundbeck, the makers of Cirpramil, said there was “no evidence” linking the drug to violence and it actually had the opposite impact. There was no increase in the risk of suicide and studies had shown no increase in violent behaviour in those who take the drug. Lundbeck Statement

Canada. Lundbeck admits to reports of self harm and harm to others. “There are clinical trial and post-marketing reports with SSRIs and other newer anti-depressants, in both pediatrics and adults, of severe agitation-type adverse events coupled with self-harm or harm to others”. Health Canada, Lundbeck Letter.

3 thoughts on “Conflicting Information on both sides of the Atlantic.”

  1. I know Ireland is an island but why is the Irish College of Psychiatry so far behind other countries in recognizing the increased risk of suicide (in all ages) with Cipramil and all SSRIs? Are they that ignorant of the scientific data? Or are they just more compromised by their allegiance to whoever picks up their tab?
    It is interesting that the Ireland Lundbeck statement denying increased risk of violent behaviour is inconsistent with the Health Canada Lundbeck letter. They need to get on the same page. Is the contradiction because the first one was in a courtroom and Lundbeck had too much to lose if they were found guilty of negligence?


  2. Thanks Julian,
    Who knows?…I have my own opinion on both as you know. The proof is there for everyone to see but money, greed and dilusional medical people who should know better all mixed together = patients kept in the dark about the very serious reactions that can occur with ssri’s and other medication.


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