Last month an Article appeared in the N.Y Times written by Carl Elliott and entitled “Useless Studies, Real Harm”… Link to full Article.
“LAST month, the Archives of Internal Medicine published a scathing reassessment of a 12-year-old research study of Neurontin, a seizure drug made by Pfizer. The study, which had included more than 2,700 subjects and was carried out by Parke-Davis (now part of Pfizer), was notable for how poorly it was conducted. The investigators were inexperienced and untrained, and the design of the study was so flawed it generated few if any useful conclusions. Even more alarming, 11 patients in the study died and 73 more experienced “serious adverse events.” Yet there have been few headlines, no demands for sanctions or apologies, no national bioethics commissions pledging to investigate. Why not?”
11 deaths and 73 serious adverse events?
Turns out this wasn’t a real study at all but a seeding study, which is basically a marketing exercise designed to get doctors to prescribe the medication. Try telling that to the families of the 11 people who died.
Gabapentin/Neurontin was originally an Epilepsy medication but is now widely used for other conditions including Pain and hot flashes (hot flushes).
Wiki; suicidal acts or violent deaths,
Gabapentin has been associated with an increased risk of suicidal acts or violent deaths. In 2009, the FDA issued a warning of an increased risk of depression and suicidal thoughts and behaviors in patients taking gabapentin, along with other anticonvulsant drugs modifying the packaging insert to reflect this. In July 2009, the manufacturer of gabapentin (Pfizer) went to trial regarding the association between gabapentin and the increased risk of suicide.
Sooo..How many deaths and serious events (caused by Neurontin) have occured in the 12 years since this study?
By March 2005, the death toll from suicides in patients prescribed Neurontin had reached 258. http://www.ahrp.org/risks/neurontinSuicide0305.pdf Over 6 years later, and this drug is still being widely prescribed, so how many deaths now?
Pfizer ordered to pay $142 million in damages for fraudulently marketing gabapentin/Neurontin. Link.
Pfizer admits Fraud with Neurontin, pays fine and sales flourish. Link.
Pfizer hit with a 2.3 billion dollar fine and admits to “intent” to mislead and defraud the public/heart attacks, stroke and angina with Bextra. Link.
Pfizer’s Zoloft and suicidal ideation. Link.
Pfizer’s Zoloft and murder/suicide. Link.
Pfizer’s Chantix, murder/suicide. Link.