This week the BBC aired a Panorama documentary titled ‘A Prescription for Murder’ which has stirred some much-needed debate on the mind-altering effects of SSRIs. The very-astute presenter Shelley Jofre is known for tackling ground-breaking medical-related issues, including ‘Who’s Paying Your Doctor‘ and ‘The Secrets of Seroxat‘. (Due to the circumstances surrounding my son Shane’s death, I make a brief appearance in this documentary. )
As expected, the documentary caused a huge furore, with many defending the antidepressants drugs they take ‘that don’t cause them to become murderers’, accusing Panorama of being irresponsible and increasing the stigma of mental illness. Indeed, psychiatrists came out in their droves with their usual defense of psychotropic drugs, with seemingly no concerns whatsoever of adverse effects – or of their profession’s incestuous relationship with the pharmaceutical industry. The possible stigmatization of the people who suffer from serious and well-documented adverse effects of these prescribed drugs never entered the debate.
Anyway, watch the documentary and see what you think. I will say what I have always said – My lovely son would still be alive if he hadn’t gone to the doctor, whose fateful decision to prescribe citalopram for heartache proved fatal. 17 days after being prescribed the drug, following a series of red-flags that the drug was causing havoc, Shane was dead.
Citalopram is an SSRI antidepressant, sold under the brand names of Cipramil in Europe and Celexa in the U.S.
Sertraline, the SSRI that James Holmes was prescribed, is sold under the brand names of Lustral in Europe and Zoloft in the U.S. It was interesting to hear Delnora Duprey speaking on the programme; In 2001, three weeks after he was prescribed sertraline, Delnora’s grandson Christopher Pittman shot and killed both of his paternal grandparents. Then there was David Carmichael, whose account of his time on Paroxetine (Seroxat/Paxil), leading to the death of his young son, is equally harrowing.
Since their inception and without exception, all the SSRI drugs have been implicated in suicides and extreme violence, including homicide. With drug-company reports of ‘self-harm and harm to others’ and regulatory warnings of suicidality, violence, mania, akathisia, worsening depression, severe withdrawal, long-term sexual dysfunction, birth defects, depersonalization, etc., the stance that these drugs are safe for all is no longer tenable.
Jeez – here we go again. Yesterday’s BMJ article that found antidepressants double the risk of suicide and aggression in young people, made headlines worldwide. From America, Australia to india, caution was advised when prescribing in this age bracket. Not so in Ireland. The one newspaper article referring to the BMJ article can be found in today’s Irish Examiner here, entitled ‘Drug link to child suicide queried by expert’. So did it warn prescribers of the suicide and aggression risks, advise stricter guidelines or just advise caution when prescribing to children? None of the latter. Instead the Irish Examiner published an article allowing Professor Patricia Casey to question the findings of the Nordic Cochrane Centre.
Coincidentally, Professor Casey was also in the newspapers yesterday, having brought a High Court action against the Irish Times for alleged defamatory comments made by the public online. The anonymous online comments stated that Professor Casey was an unprofessional psychiatrist who was unfit to treat suicidal pregnant women and further, that she misrepresented psychiatric research in order to promote a Catholic agenda. The Times kowtowed apologised and the action was settled between the parties; therefore, no legal precedent was established. Professor Casey’s legal letters are legendary and many, including me, have been on the receiving end. Whatever happened to ‘truth’ and ‘honest opinion’ being defences to defamation?
Furthermore, regarding the comment that Professor Casey is pushing a Catholic agenda. Similar to defending antidepressant use in children, she’s certainly not pushing a Catholic agenda when she says antidepressants can be life-saving in pregnancy, while keeping quiet about the harms SSRIs can cause to the foetus, an issue that she’s well aware of. Another scientist (and psycho-pharmacologist) David Healy, has brought to her attention that these drugs can increase the rate of abortion, miscarriage and birth defects – but Professor Casey chose not to explore the data. May God forgive us all..
As for the BMJ article, far be it for me to contradict Professor Casey, so I asked the scientist at the centre of the study, Peter Gøtzsche, what his thoughts were on her Examiner article. See his detailed reply (in blue) below –
Prof Casey, however, said the jury was still out on the risks and benefits of prescribing the antidepressants, commonly known as SSRIs.
She believed psychiatrists dealing with children and adolescents should decide on a case-by-case basis.
“If a child is depressed and is not responding to evidence based treatment on offer, like talking therapies or some other anti-depressant, the psychiatrist might only then go and prescribe the SSRIs,” she said.
I consider it bad medicine to use antidepressants in children. They don’t work, according to the children themselves when asked in placebo controlled trials, and they double the risk of suicide and treble the risk of aggression.
“I am not a child or adolescent psychiatrist — I deal with adults. But I know from speaking to colleagues that there are differing views on prescribing SSRIs. Some say no, SSRIs should not be prescribed while others say, yes, we should, otherwise there will a greater risk of dying by suicide.”
Psychiatrists who claim that antidepressants protect children from committing suicide should not be allowed to practice; they are too dangerous to have around.
Prof Casey said it was found in the US and in the Netherlands that the suicide rate in children and adolescents increased after members of that group stopped being prescribed SSRIs.
All such studies have been found to be seriously misleading. I explain why in my recent book, Deadly Psychiatry and Organised Denial. The randomised trials provide far more reliable evidence and they show that the suicide risk doubles when children get antidepressants, which is why the drug agencies warn about using these drugs in children.
This was noticed particularly in the Netherlands, where the drugs carry a ‘black box’ warning.
Critics quickly pointed out the dishonest science that Gibbons had employed to make this case. He reported that SSRI prescriptions to youth declined by 22% in the U.S. from 2003 to 2005, and that suicide rates in youth rose 14% between 2003 and 2004. But since he had only the suicide rates for the U.S. through 2004, he should have focused on prescribing rates during that same period of time.
In fact, there had only been a very small decrease in the prescribing of SSRIs to youth between 2003 and 2004, when the number of suicides rose. It was between 2004 and 2005 that the there was a significant decrease in the prescribing of SSRIs to youth, and–as the critics noted–once the suicide data for that period became available, it showed that during that time, the number of suicides for persons ages 5 to 24 declined.
In other words, the data showed that as the number of prescriptions to children and youth declined, the number of suicides in this age group declined too. But Gibbons reported that the opposite was true. He did so by matching the increase in suicides in 2003-2004 to the decline in prescribing in 2004-2005. This is not the sort of error a scientist “accidentally makes.” This is the sort of presentation of data one makes when he or she is trying to deliberately tell a story that fits a preconceived end.
In the Netherlands, Dutch academics were incensed with Gibbons and his statistical antics. In the Dutch Drug Bulletin, they noted that the increase in suicides in the Netherlands was so small that it was “not statistically significant.” They described his conclusions as “astonishing” and “misleading,” and stated that Gibbons and his co-authors had been “reckless” to publish such claims.
“Child psychiatrists should not be eliminating SSRIs totally from their armory but using them when other treatments don’t work because there is now clear evidence of an increase in suicide in young people that appears to approximate to the time when the reduction in their prescription occurred,” said Prof Casey.
This is total nonsense. There are no reliable studies that have shown this. And interestingly, when the usage of SSRIs went up in the UK in youth, suicides in youth also went up, but no one has felt compelled to publish a paper about this, as far as I know. Selective reporting is certainly an issue here.
However, the research led a British expert to call for stricter prescribing rules.
Professor of evidence-based psychological therapies at University of Reading, Shirley Reynolds said only specialist child and adolescent psychiatrists should prescribe antidepressant medication to children and young people.
No. No one should prescribe antidepressant medication to children and young people. I consider this a medical error. They don’t work and they are harmful.
“Obviously these results will make doctors, parents and young people themselves think harder about taking antidepressant medication,” she said.
They need not think hard. They should just say no. This will save many lives.
“But do the results mean that children and young people should never be prescribed antidepressant medication? No.
Yes! It should be forbidden to use these drugs in children and young people. We also need to face the fact that these drugs can cause suicide at any age, and they can also cause homicide.
My attention was drawn recently to an Irish Catholic article involving Professor Patricia Casey, well known Irish psychiatrist and IONA Institute patron (conservative Catholic advocacy group). The article ‘Simplistic therapy approach to suicide criticised in new study’ was published in the ‘Irish Catholic’ and centers on a study published in the Irish Journal of Psychological Medicine. The study Psychiatric and psycho-social characteristics of suicide completers: a comprehensive evaluation of psychiatric case records and postmortem findings is based on toxicology tests done post mortem and expresses the opinion that people dying by suicide were not adhering to their treatment (drug regime). The journal itself is the official journal of the ‘College of Psychiatry of Ireland’ – the same college which I have previously shown to engage in some dubious practices. While sending an ‘internal’ college e-mail to its members (regarding my son’s death where an antidepressant was implicated), it also forwarded the same literature to the drug company in question. While I have queried the ethicality of the latter with the college of psychiatry, no satisfactory answers have ever been forthcoming.
Leaving aside my possible subjectivity on the college’s questionable ethics, the article itself raises other relevant issues. Toxicology results post mortem are notoriously unreliable (Drummer et al 2004) and should not, as yet, be relied upon to conclude drug concentrations before death. I personally know of mothers who have lost their sons to antidepressant-induced deaths where the antidepressant escaped detection in toxicology tests. Two of these mothers vehemently objected and insisted on a re-test – in both cases the drug was eventually detected, once on the second time and once on the third time.
Firstly, as the basis of the study relies on toxicology results, the reliability of toxicology tests post mortem was not addressed in the study.
Secondly, even if these toxicology tests were 100% reliable, it raises other important questions – how is it that 1/3 of the people who died by suicide were taking their medication? Were the drugs at best ineffective or at worst a causal factor in these deaths? It is noteworthy that the suicidality warnings included in antidepressant PILs (patient information leaflets), were put there, not by any well-meaning intentions of the drug industry, but by order of the FDA (American Drug Regulator) and EMA (European Medicines Agency) following lengthy investigations.
Lastly, again in the case of the toxicology being 100% effective, how many of the victims were in withdrawal from these highly toxic drugs? Treatment-induced (and withdrawal-induced) suicide has been discussed in another study (Healy et al 2006). This possibility has led regulatory authorities to warn doctors about the risk of suicide in the early stages of treatment, at times of changing dosage, and during the withdrawal phase of treatment. Was ‘withdrawal’ a simple oversight on behalf of the original study authors?
It seems to me that the Irish Catholic and the IONA institute have bigger fish to fry – treatment of the living for example. Considering the current abortion debate raging in Ireland, it strikes me as strange that the pro-life IONA patrons have not addressed the issue of the widespread treatment with antidepressants in pregnancy. Speaking last year on the problem of assessing suicidal pregnant women, Professor Casey said “Who will offer her the first-line treatments (antidepressants and/or cognitive therapy) she so desperate needs?” That antidepressants save lives is not evidence based(Healy 2006) and problematic in pregnancy according to Adam Urato (personal communication, June 29, 2015), expert in Obstetrics & Gynecology and Assistant Professor at Tufts University School of Medicine. He stated –
“The antidepressants freely cross over the placenta and into the developing fetus (baby) throughout the pregnancy. They have significant harmful effects for moms and babies including miscarriage, birth defects, preterm birth, preeclampsia, newborn complications, and long-term neurobehavioral problems. These chemical compounds—what we call antidepressants—are made in chemical factories and they go from these factories, into the pregnant moms, and then into the developing babies (fetuses). Nowadays, with 5 to 10% of all pregnancies being exposed to these drugs, what we are basically witnessing is a large scale human experiment. The track record of what happens when we expose developing babies to foreign chemical compounds is not good. Chemicals have consequences for developing babies.”
Rather than focusing on dead people, the IONA Institute need to address treatment-induced fetal harm or it could be left wide open to accusations of hypocrisy. Suffer little children – a thorough investigation by the ‘Irish Catholic’ might be a good place to start.
Drummer O, Forrest ARW, Goldberger B, Karch SB, International Toxicology Advisory Group. Forensic science in the dock: Postmortem measurements of drug concentration in blood have little meaning. BMJ : British Medical Journal. 2004;329(7467):636-637
Healy D, Herxheimer A, Menkes DB. Antidepressants and Violence: Problems at the Interface of Medicine and Law. PLoS Medicine. 2006;3(9):e372.
Healy D, The antidepressant tale: figures signifying nothing? Advances in Psychiatric Treatment. 2006,12 (5) 320-327
Strange to be writing about someone who’s alive, but a nice change all the same. A survivor, who knew? Sorry, sarcasm – you can take the girl outta Sallynoggin…
Gareth O’Callaghan is a well known Irish author, radio presenter and mental health activist. He has written numerous books on depression, including the popular A Day Called Hope: A Journey Beyond Depression. Recently, he has spoken out about his experience on the SSRI Citalopram (aka Cipramil/Celexa), the same drug my son Shane was on for 17 days before his death. Why he has decided to bare all now, I don’t know, but I’m just glad that he has. Gareth said that he followed Shane’s case avidly “..not only because of the huge media coverage it received, but also because I too took citalopram many years ago. I can identify with the Akathisia (restless, aggressive inner anxiety) that Shane suffered as a result of the drug. I could really frighten people here if I was to explain in detail what Akathisia does to the mind. Thankfully I had a chance to stop taking the tablets. Shane didn’t”.
I should say that this is not news to me – I spoke to Gareth some years back; he’s a nice, friendly and very honest guy, who pulls no punches. He can be heard on 4FM every weekday afternoon here.
Akathisia (from the Greek for inability to sit) is a widely misunderstood and underestimated adverse effect of taking a drug, usually an SSRI antidepressant or a benzodiazepine. Coded in Patient Information Leaflets (PILs) as ‘inner restlessness’ and ‘restless leg syndrome’, it has been described by some survivors as the ‘worst experience ever’, a feeling of ‘inner torment’ where ‘death would be a welcome release’ and seems ‘the only, very welcome option’.
Wendy Dolin, who I had the pleasure of meeting in Copenhagen, described how her husband Stewart died while suffering with akathisia – 6 days after he was prescribed Paxil/Seroxat. She has set up MISSD, a blog specifically to warn of the dangers of akathisia –
“On July 15, 2010, (six days after beginning the medication), following a regular lunch with a business associate, Stewart left his office and walked to a nearby train platform. A registered nurse who was also on the platform later reported seeing Stewart pacing back and forth and looking very agitated. As a train approached, Stewart took his own life. This happy, funny, loving, wealthy, dedicated husband and father who loved life left no note and no logical reason why he would suddenly want to end it all. Neither Paxil nor the generic version listed suicidal behavior as a potential side effect for men of Stewart’s age.”
A recent post on MISSD reports a personal experience similar to Gareths here. David Healy also explained akathisia in his coroner’s report for Shane’s inquest here. Short excerpt below –
There is good evidence that akathisia can exacerbate psychopathology in general, and a consensus that it can be linked to both suicide and violence. A link between akathisia and violence, including homicide, following psychotropic drug use has previously been reported.
What surprises me with Gareth’s post, is that while he is telling of his awful experience and has many supporters, some people have taken offence where there is none intended. There are quite a few ‘how dare yous’. It seems that while it’s perfectly acceptable to be MedicatedAndMighty, it’s not okay to be UnMedicatedAndMighty and talk of a bad personal experience with prescription drugs. Surely his story is equally important? A selection of the comments below:
you’re doing more damage by labelling those who need help
I am going to unfollow u I have had enough of your one sided beliefs
Please don’t make people feel bad If they need it after bereavement etc.
Giving drugs for bereavement is surely part of psychiatry’s problem but one I won’t go into here (See works of David Healy, Robert Whitaker, Peter Gotzsche, Peter Breggin, etc). It should be noted that akathisia is not always fatal but monitoring is crucial. If it occurs in the early stages of taking a prescription drug, it can occasionally wear off (but not always). If it develops later, it’s less likely to wear off.
Read Gareth O’Callaghan’s post on akathisia below; It’s well worth a read..
This is a true story. It is called personal experience. It happened to me. In hindsight it relates to probably the most terrifying month of my life and I would like to write about it here for the first time. It happened 16 years ago.
If you would prefer not to read how an antidepressant can destroy a human mind, and even kill, then I suggest you stop here. Otherwise please read on. It’s also worth remembering while you’re reading this that there have been hundreds of suicides in Ireland so far this year. Many of these people could still be alive if they had been told the truth about these drugs before they had been prescribed.
I have written here on a few occasions about a condition – a body and mind reaction – called ‘Akathisia’, which is directly caused by antidepressant medications. I would like to explain more about this dangerous reaction this evening and what it really is, as very few people have ever heard of it. And it is one of the most dangerous and severe side-effects of these drugs.
In 2000 I was diagnosed with depression and prescribed citalopram (aka celexa, cipramil), a drug that – to the best of my knowledge – arrived in 1996. It was still brand new. These days we now know it is also extremely dangerous as I will explain in a moment. Despite all the damaged lives it has caused and the many deaths it has been responsible for, it is still one of the most frequently prescribed antidepressants from a range of drugs known as SSRIs (selective serotonin re-uptake inhibitors). Why, if this drug can induce death, is it still widely available?
Back then we knew nothing about what this toxic drug was capable of doing because it was basically still being tested. 16 years ago most of us might agree that our education about mind-altering drugs was scant and strongly influenced by the medical profession. Consequently very few of us were prepared to share our experiences like we are today because we knew no better. We were led to believe this was ‘the cure’.
The SSRIs have for years been marketed around a shocking blatant lie, namely that a chemical brain imbalance causes depression. Back then, 16 years ago, I thought (as a result of buying into this myth) that this drug would rebalance my brain chemicals and cure my depression. If only I had known back then what I know now.
I was told that the drug would take between three and five weeks (maybe six) to really ‘kick in’. I was told to be patient. So I reminded myself each day through this anxious misery and baseline unhappiness that I was feeling that I would eventually see the sun again and appreciate the life I had forgotten existed. I waited. And waited. And then after about seven days my life changed. Something truly shocking and off-the-scale of understanding started to happen.
I started to feel more anxious, in a stomach-knotted nauseous kind of way. My heart started to beat faster and I felt like I was losing my grip on reality. My first panic attack happened in a packed shopping centre on a busy Saturday afternoon. I lost the plot. I felt like I was having some sort of seizure so deep inside me I couldn’t control my rational self.
I told my two young daughters that we needed to get back home as quickly as possible. They couldn’t understand why I couldn’t explain why we needed to go home. I was cracking inside very quickly, sweating, trembling, palpitating, even crying. I was losing all sense of reality in a way that was terrifying me. How I managed to drive home that day is still something I can’t bear to think about.
Once home I went upstairs to a room which I had converted into a small office years before, closed the door and started to cry. The crying became a full-scale panic attack and I ended up lying on the floor hugging my knees trying to stop the awful sensation of severe agitation that was tearing me apart inside.
Eventually it eased; but then the pain in my knees became so bad I had to get up and walk around. It wasn’t normal walking; it was pacing. I paced around the house, often sitting down to rub the pain out of my knees, and then standing and pacing while scratching my face and squeezing my abdomen to stop the horrendous agitation that was tearing at my gut. It was so deep inside me it was tearing at my gut with a hidden pain I couldn’t reach.
In the days that followed, the aggression I felt would play horrible games with my mind. I couldn’t be around sharp instruments, or walk near water. I found it increasingly difficult to cross busy roads, or to be in a crowded place for more than a few seconds. Panic struck me randomly. I was afraid to drive my car so I stopped driving. But most of all the desire – the irrational, unwanted, terrifying need – to kill myself was never far from my mind. Death would stop this pain but I didn’t want to die, I kept thinking. My brain was in a state of meltdown. The nightmares and the sweats were truly shocking.
I lasted for three weeks on citalopram. On the 22nd day I rang my doctor. I told him I couldn’t take it anymore. I explained to him what was happening and he was shocked. I am lucky to have a very good doctor. Many people are not so lucky.
If reading about my experience here has upset you, then please let me emphasise that this was never my intention. This may not help you but I hope it might help someone who is reading this tonight and possibly going through this awful ordeal.
I made a promise to myself years ago that I would be totally honest with myself. If I can’t be honest to me, then I definitely can’t be honest with you. My writing comes from an honesty that believes in justice and support for others who are coming through what I have come through.
I know so much more these days about mental health and what heals, and also what doesn’t. I knew nothing back then. I started to educate myself when it dawned on me just how close I had come to harming myself seriously.
Unfortunately unless you have a good doctor you probably won’t be told what you need to hear and do. That is just not acceptable. If your doctor is a dickhead, get a new doctor – simple as that. If your psychiatrist is more interested in spoofing than in healing, then leave the room.
Akathisia, we are told, is usually a ‘mild reaction’ to SSRIs. Let’s be honest here. Mild is an understatement. For many people who start these drugs, akathisia is a life-threatening condition that needs to be more fully understand by both patient and doctor.
Most psychiatrists play it down because they know that three of the most popular drugs that they claim to be suitable and ‘safe’ to take for depression, that they increasingly peddle as a cure (the same drugs they include in many of their speculative, dodgy concoctions) cause akathisia: FACT.
These three drugs are Prozac (fluoxetine), Seroxat (paroxetine), and Cipramil (citalopram/celexa).
These drugs are believed to play havoc with the brain neurotransmitter norepinephrine, which under normal conditions is secreted in response to stress. It is associated with levels of insomnia, anxiety (panic), and aggression (and violence).
Research has shown that these drugs make people ‘more prone’ to suicide (and aggression) during the first few weeks of starting to take them. So many people suffer silently from akathisia. Ask any of these people if they were experiencing these awful side-effects before taking the drugs and they will tell you most likely they were not.
A deep sense of loss of interest in life, a deep-rooted unhappiness, a feeling of morbidity … these are all feelings of depression; but unfortunately often the very drug that is taken to counteract these feelings creates a violent emotional storm that many psychiatrists (and doctors) blame on the depression – not the drug.
Psychiatry is not going to change its attitudes to SSRIs. The pharmaceutical companies who developed these drugs need psychiatrists and doctors to keep selling them. Big Pharma has too much to lose. They don’t want you to find another way of healing your life. They want you to be as depressed as you possibly can be. Otherwise their profits drop because they can’t peddle their drugs. (And that’s beginning to happen.)
If a young person dies while on their drug, they blame the so-called illness, not the toxic drug. Depression is a multi-billion euro business. The second biggest exporter out of Ireland is antidepressants.
Maybe you haven’t experienced anything like what I have just described. If so, you are one of the lucky ones. If you have any doubt or bad feeling about the medication you take, or have started to take, then go straight back to whoever prescribed it to you. Demand honest answers to your questions. You are paying a lot of money. In return you are also demanding respect.
If they tell you that you are “blowing it out of all proportion” (as one young man told me he was told by his doctor), or to “stick with it”, as others have been told, or if they tell you they know best, then change your doctor. Get someone who genuinely wants to help you. It might just save your life.
Today I attended the inquest of Jake McGill Lynch, which concluded with the Coroner returning an open verdict. Firstly, amid all the legal argument, there was an infinitely more important factor; Jake..
In 2012 Jake was diagnosed with aspergers syndrome; he was just that ‘little bit different’ ye see. He was a little too intelligent; too good; too kind; too perfect to be perceived as a ‘normal’ disruptive adolescent. I often wonder why psychiatry gets to define what is ‘normal’, considering the lack of any scientific tests to determine otherwise. Are we not all individuals with traits that others would see as abnormal? Are our strange and weird traits not what makes us likable, or even unlikable? Sure, Jake liked routine and things to be in order, a place for everything and everything in its place – not a bad trait I’d say, but nowadays it’s ‘diagnosable’. This extraordinarily intelligent young man was diagnosed, labeled forever, for being just that little too perfect.
Jake was an articulate, handsome young man. He had an online girlfriend, loved to play with his Lego and like ‘normal’ 14 year olds, spent hours on his beloved Xbox. He had joined a gun club with his mam and idolized his big brother and little dog Charlie (equally). He loved his native language and was a fluent Irish speaker.
Jake was primarily a happy camper with few problems, apart from feeling a little anxious on stressful occasions. He was attending a counsellor to help with his feelings of anxiety. When the counsellor decided that Jake didn’t need any more sessions as he was “the happiest she had ever seen him”, she referred him to a psychiatrist. His mam thought that this referral was in order to sign Jake off. Inexplicably, instead of signing Jake off, the psychiatrist prescribed Jake an SSRI Fluoxetine (aka Prozac), to ‘help with his exams’. Neither his mam or dad were given a patient information leaflet (PIL) or any information on side effects – suicidality or otherwise. Therefore, they were not told that SSRIs, including Prozac, doubled the risk of suicide.
Jake’s medication was doubled after a week, without seeing the prescribing psychiatrist. He became increasingly restless and had a meltdown in school which was totally out of character. 46 days after his prescription for Prozac, Jake’s parents found him on the floor of his bedroom – he had shot himself in the head with his legally held rifle. He was rushed to hospital but declared dead a short time later.
The psychiatrist had previously testified that she prescribed Jake with Prozac ‘to help with his exams’ because he had had ‘a meltdown’ while doing an Irish exam. This off label prescribing is truly shocking, but what is worse is the fact that Jake’s ‘meltdown’ occurred 5 days AFTER he was prescribed Prozac, not before. Why would a doctor get this so wrong? Is covering their own backsides more important than revealing the true circumstances surrounding the death of a 14 year old child? Do Jake’s parents not deserve to be presented with all the facts, not a cover-up? The HSE’s barrister spends a lot of time in the Coroner’s Court – he’s obviously very good at what he does. Personally I think an apology would be far cheaper. Jake, the 14 year old child in the middle of all this, seemed to get overlooked in copious legal argument.
The Irish drug regulator, HPRA, states that ‘Prozac is not for use in children and adolescents under 18’ here. The HPRA further states that if Prozac is prescribed off-label to a child over 8 (Sweet Jesus) with ‘moderate to severe major depressive disorder’, that it should be offered only in combination with psychological therapy. JAKE DID NOT HAVE DEPRESSION! In 2005 the Committee on Human Medicinal Products, CHMP, advised that SSRIs ‘should not be used in children and adolescents except within their approved indications – not usually depression – because of the risk of suicide-related behaviour and hostility’. If prescribed off-label, the CHMP recommends that patients should ‘be monitored carefully for the appearance of suicidal behaviour, self-harm or hostility, particularly at the beginning of treatment’. Why then was Jake’s prescription for 10mgs of Prozac doubled the following week, without even seeing the psychiatrist? I would not call that careful monitoring.
What was particularly grueling for the family, was the 13 appearances in the Coroner’s Court, mainly for legal arguments over whether the family had a right to call an expert witness (David Healy). Not surprisingly the HSE barrister was vehemently opposed to David Healy taking the stand, stating that if he was allowed to be the family’s ‘expert witness’, they (the HSE) had an ‘expert witness’ who would say the opposite. I’m sure they had! The coroner refused the family’s request, referring to the limitations of the Coroner’s Act 1962 and the case of Eastern Health Board v Farrell, but said he’d have no objection to the family having an expert to ‘advise’ them on the day. By this stage Dr Healy was in the US, so Declan Gilsenan (retired assistant state-pathologist) came to the rescue and stepped in to advise Jake’s family. He has publicly stated “Based on my experience of doing postmortems on people where anti-depressants have been started fairly recently I would have concerns about the link to suicide”.
It is of particular significance, that in May 2012 Dr Gilsenan attended Leinster House with Dr Healy, warning that these drugs were causing many deaths and asking for an investigation to be initiated. Nothing was done – NINE months later Jake was given a prescription for Prozac and the cycle continued.
What was awful today, apart from hearing the circumstances of Jake’s death, was looking into the faces of his grieving parents. That familiar look of unbearable pain etched on their faces, the unbelievable loss of their son who had so much to give – all totally avoidable. Another Irish boy lost through psychiatric drugs and another doctor being permitted to recollect ‘facts’ that just don’t add up; another mom and dad left bewildered and lost; another year, another death and still our Ministers avert their eyes and do nothing. Shame on them and the Irish Government.
The coroner, having heard arguments for the rights and wrongs of prescribing Prozac in children, said that it was “beyond his capabilities to adjudicate on Fluoxetine” but could not ‘beyond reasonable doubt’ say that Jake intended to take his own life. He then rejected a suicide verdict and returned an open verdict.
Dia leat Jake. Ní dhéanaimid dearmad ort go deo.
The last word must go to Jake. It clarifies exactly what his family have been fighting for. In an e-mail the night before his death, he said (verbatim).. “The ‘anti-anxiety’ stuff is actually an anti depressant which they didn’t tell me. Probably doesn’t make much of a difference, but I feel like I’m drugged to the point that it suppresses everything bad until it suddenly spills out.”
Not too sure what to make of this. Truthman recently wrote a blog ‘Will The Real Ben Goldacre Please Stand Up’. Mr Goldacre is a psychiatrist and author of ‘Bad Pharma’, a book on the misdeeds of the pharmaceutical industry. What Truthman was saying was that Goldacre’s book was just a rehash of other books which came before it, eg., David Healy, Marcia Angell etc – ah feck it, it’s too hard to explain; read his blog here.
The thing that surprised me most was Goldacre’s comment on Truthman’s blog. He’s not one to shy away from an argument it seems, although Truthman did refer to Goldacre’s book as ‘impotent’ and you know how sensitive men get with ‘that’ word. He also alluded to Goldacre’s involvement or ‘non-involvement’ with GlaxoSmithKline’s supposed transparency decision; in my opinion, a non-existent publicity stunt by GSK.
I thought that Goldacre was a little churlish bringing David Healy into his comment, although then again, Truthman did mention the latter’s review of the book at issue: “An insightful (albeit also complex) review of Bad Pharma from David Healy (not so bad pharma) seems to conclude that the problem with Bad Pharma rests not upon the repetition of content already covered, or the many flawed arguments raised which seem to rally against the pharmaceutical industry but actually often work in their favor, “but on the premium Ben puts on controlled trials not found in other books”.
Truthman is a very intelligent writer, whose research is usually impeccable. On this occasion he seems to have rubbed Ben Goldacre up the wrong way. This is a very interesting and enjoyable read (handbags at dawn) but I’m afraid you’ll just have to make up your own mind – Will The Real Ben Goldacre Please Stand Up?
At the risk of repeating myself; In May last year David Healy and Declan Gilsenan met with Kathleen Lynch in Leinster House (Government Buildings). David Healy told her that psychiatric drugs were the leading cause of death within the mental health field. Declan Gilsenan had similar concerns. So naturally she acted straight away, right? Wrong, nothing has been done!
Last Thursday the body of a 71 year old man was found dead at his home in Cloyne, County Cork. Alan Lee was reported to be a reserved bachelor who lived alone and kept to himself. Newspaper reports stated that Mr Lee was found in his kitchen with over 30 stab wounds. The incident is now being treated as a self-inflicted tragedy. What none of the on-line newspapers have revealed is that Mr Lee was recently treated in a psychiatric unit in Cork. Not one stated that he had just been released from a psychiatric hospital earlier on the same week. The hard copy of the ‘Irish Times’ reported these details (Sat 9th Nov).
Mr Lee is not the first person to have died shortly after his interaction with Irish Psychiatry, whose ‘medical model’ (pill-pushing) is the first line of action in vulnerable people. People who come looking for help, instead get mind-altering drugs which double the risk of suicide and violence. There are many deaths happening within the psychiatric ‘services’, some which I’m not at liberty to discuss. Yet, some have been publicly reported in the media this year. In March two young people went missing from St John Of God Hospital in Dublin, Kieran McKeon, 18, and Alexandra O’Brien, aged 21. It was later discovered that they had both traveled to Derry and had both jumped from the Foyle Bridge, where their bodies were eventually recovered.
What of the actor Gerry McCann? He was also being treated for anxiety in Dublin’s ‘St John of God’ Hospital earlier this year, when he went missing. His wife said his disappearance was ‘totally out of the blue’. Sadly, in September his body was found on Dollymount Strand. Gardaí said his death was being treated as a ‘personal tragedy’.
So that’s four deaths this year alone (at least) of people who have gone looking for help, and instead have died in tragic circumstances. What duty of care is owed by these hospitals to the people looking for help? One thing is for sure, the over-medicating of the masses is not working. Who stabs himself 30 times? A man on mind-altering drugs, that’s who. Depression is not a fatal disease, but the drugs used to treat it can kill. Let’s hope the families of these people will carry out their own investigations; the benefits in these four cases did not outweigh the risks.
There’s been an interesting development today in the ‘Sherif Sultan’ Saga.
Remember, Mr Sultan is the consultant in Galway who received an official warning from the HSE for speaking out on the dangers of taking statin drugs? This followed the publication of his paper here-The ugly side of Statins. He said what David Healy has been saying for a long time, that he and his colleagues “are fed up with trial of organizations to cover up truth about the ugly side of statin because of invested interest and commercial sponsorship.”
The picture you may think is a random one, but no, it’s a reminder (no pun intended) that the FDA have recently added ‘memory loss’ to the ever growing list of serious statin adverse effects.
So Mr Sultan was slapped with a gagging order (aka ‘STFU’ order) by the HSE. Did he accept this lying down? No he didn’t! Was he willing to keep taking the paycheck and stop warning his patients that statins are dangerous and usually unnecessary? Nope! What he did say was “Odds are greater than 100 to 1 that if you’re taking a statin, you don’t really need it” and further “We are observing the revealing of the ‘utmost medical tragedy’ of all times. It is extraordinary that the healthcare industry has inadvertently induced life-threatening nutrient deficiency in millions of otherwise healthy people.”
Thankfully the Irish Hospital Consultants Association (IHCA) have stepped in. Replying to the 2 senior executives, the IHCA have asked for the gagging order to be revoked. According to the Irish Independent, the reply states that there is “no provision in a hospital consultant’s contract to check with their employer the content of any comment they want to make to the public” and further that consultants have an “ethical, legal and moral obligation to advocate on behalf of their patients”.
Are we seeing the start of a revolt, an ethical army led by Mr Sultan? I sure hope so. The pharmaceutical influence in the ‘illness’ profession has reigned and dictated for long enough. It’s about time that someone stood up to Goliath. Will it be David again, or Sherif, or hopefully both? Who could have foreseen that the revolution would start in Ireland?
So the next time your doctor insists that you need that box of Pfizer pills or Lilly drug, ask him/her what he thinks of that surgeon in Galway who said “in Healthy patients with no cardiovascular history, statins have no proven benefit – in medical terms no scientific evidence for the use of statin in primary prevention.”
The meeting was chaired by MP Jim Dobbins who has previously aired concerns about the pharmaceutical industry and its close involvement within academia, such as the case with Professor David Nuttcase Nutt here. I don’t really have an issue with Professsor Nutt, other than with his false declaration to the Nation (on BBC radio) that ‘it’s impossible to kill yourself with an overdose of SSRI antidepressants‘. Dr Ciara Kelly said the same thing here on Irish radio. Very dangerous propaganda!
Anyway, I’m rambling off the point again this morning. Suffice to say, as is usual, our trip did not always go as planned. We decided, as we were going to London for this talk, to bring the kids with us and maybe go to Legoland the following day. We had plenty of time as the flight was an early one and the talk wasn’t on until 2pm in Westminster. The Ryanair plane sounded decidedly dodgy, as if it was running on dirty fuel (haha, Tony will tell you I have a good mechanical ear) and unsurprisingly the pilot decided that we would have to change planes. This left us two hours behind schedule so the pressure was on, the kids were happily oblivious but the odds at arriving on time were stacked against us. In stepped my brother-in-law in his superman underpants in order to save the day and meet us in London Bridge. He took the kids to my sisters in Kent (where we were staying with 3 cousins, all girls and under the age of 3). This left us plenty of time to head to Westminster for the talk. Back on track.
There was nothing I could do about the frizzy hair at that stage but I thought I’d better change out of the tracksuit bottoms. I decided I would have to change into my ‘Westminster’ clothes in the toilet on the train. Yep, that sounds like a good idea you think? Thanks, I thought so too. The toilet doors were of the circular kind which we have here in Ireland too. There was a nice man sitting outside the toilet when I went in, who smiled at me and said hello; the English are so polite aren’t they? So I took the boots and tracksuit bottoms off and was standing in my underwear (thank God for small mercies) when the train jolted and I leaned backwards, for balance you understand. I leaned on the open-door button, which promptly left me standing in my knickers exposing myself to the poor man sitting outside. Frantic pressing on the buttons failed to close the doors for a lifetime of seconds, until the doors finally closed on the man’s shocked expression. I debated whether I could stay in the toilets until the man either got off or died from old age, whichever came first, but eventually braved the situation and departed from the toilet where I grinned at him in a stupid fashion. He couldn’t look me in the face and glanced quickly out the window. Oh well, nobody was arrested and Tony’s well used to my little accidents/incidences.
So having laughed our heads off all the way to Westminster, we finally made it with a half an hour to spare. After the talk was over, we retired to another room where a question and answer session took place. Jim Dobbins actually voiced what we all knew all along, that the pharmaceutical industry has the Government over a barrel and if the Govt were to sanction ‘industry’, they would threaten to take their business elsewhere, hence GSK et al having control in the UK. This is no doubt the case in Ireland where industries influence is palpable everywhere. If pharma can have such a huge influence over the UK Government, what chance do we have over here in our small country with a population of 4.5 million citizens and with a proven history of unscrupulously corrupt Ministers? You would have to wonder why Kathleen Lynch and James Reilly have done nothing about SSRI-induced deaths.
David Healy’s talk was brilliant as always. We also had the pleasure of meeting the lovely Brian of AntiDepAware and his equally gorgeous wife. We met with Bobby Fidd which is always a pleasure but who missed the chat afterwards having commandeered my poor husband to go outside for a smoke, and who subsequently both got lost.
The 3 gorgeous girlies under the age of 3 were hilarious, funny and little dotes. I don’t know how any household survives them, but I actually miss them already!
PS. The LegoLand experience was amazing and went without any major incident thankfully. All children accounted for, happy and alive, which is more than I can say for my eldest son’s involvement with Lundbeck pharmaceuticals and some uninformed Irish doctors.
Bob Fiddaman’s account of the meeting can be read here, while Brian’s can be read here.
There are some very, very tragic cases being publicly played out in Ireland at the moment. Whether the use of medication was a factor or not in these cases has not yet been established, but the following unusual case came up in the Irish courts recently.
On 22nd of July Nurse Greta Dudko (pictured) pleaded not guilty to murder but guilty to the manslaughter of her mother ‘Anna Butautiene’ on Christmas Eve 2010. The jury failed to reach a verdict and a retrial was set for Oct 2014.
Ms Dudko, who is originally from Lithuania, had separated from her husband two weeks before the incident and was living with her mother and young son. Evidence was given of a litany of mitigating circumstances, including assault, both mentally and physically, resulting in the mother being struck twice over the head with a bottle by Ms Dudko. She said “I hit her on the face with the empty bottle twice because I thought she was going to ruin my life and just hated her,” She further stated she had no intention of killing her, “just to shut her up for the evening“.
Despite huge media coverage, only one newspaper reported that she had recently been prescribed medication by her GP, Dr Hassan Albayyari. On 15 December 2010 Dr Hassan prescribed Librium for alcohol withdrawal (9 days before Ms Dudko caused the death of her mother). Librium, a benzodiazepine, can cause, among other things: depression, thoughts of suicide, unusual risk-taking behavior, decreased inhibitions, no fear of danger, confusion, hyperactivity, agitation, hostility and hallucinations. There was further evidence of a prescription for Xanax in September 2010.
On December 22, 2010 (2 days before her mother’s death), she was prescribed Lexapro. Yes, Lundbeck’s Lexapro aka Escitalopram, found by a Brussels court to be the same as Cipramil aka Citalopram, here. Now, it is well established that this drug can cause ‘self harm and harm to others’, which at worst equates to suicide/homicide, so is this a prime example of involuntary intoxication? Dr Hassan said “Lexapro takes a minimum of three weeks to work”`. According to Professor David Healy who is an expert on SSRIs, that is wrong. In his paper entitled ‘Antidepressants for Prescribers‘ he states “This is completely untrue. These drugs produce benefits and harms within hours or days of first taking them. It may take several weeks for a clinical syndrome to lift but this is something quite different. The argument that the drug takes time to work is trotted out as part of the defense against claims that an antidepressant has triggered suicide or violence.”
So is Dr Hassan defending the use of Lexapro in this case? Who knows, but here is a list of some similar cases where antidepressant use was successfully used in an ‘Involuntary Intoxication’ defense, here.
There is also a further paper written on this subject by David Healy et al, entitled ‘Case Histories As Evidence’, here. Sadly, this paper refers to my son Shane (who is SC) and who suffered from involuntary intoxication of prescribed Citalopram. Is Nurse Greta Dudko another Lundbeck victim to add to the growing list, along with her mother?