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BMJ – Antidepressants double suicidality and aggression in children and adolescents.

Woman studying and relaxing

I’ve been neglecting my blog recently and must say, I’ve missed it. I find blogging very therapeutic but have had to forego the rantings in order to study for a masters. Whose bright idea was that? While some people find it relaxing to visit the spa, go jogging (requires too much effort) or veg on the couch with the latest ‘Top Gear’ and a Tesco’s bag stuffed with chocolate and jellys (the poor unfortunate husband) – I like nothing more than having a few hours hunched over the computer (blissfully oblivious to the lads running amok in the background), ranting about what occasionally interests or annoys me. The thing about becoming a mature(ish) student is that there are always essays to be submitted. Timely and well-researched masterpieces take time and effort, I’ll have you know! Having finished my first assignment and mastered (kind-of) the intricacies of Endnote (no mean feat), my time is my own for a few days. I’m still not quite over the shock that this quare one from Sallynoggin was accepted into The Royal College of Surgeons. I kept telling the husband that Sallynoggin people are superior beings but he never believed me, although, I keep expecting the professor to barge through the door and say so sorry Ms Fennell, we got the rejected pile of applicants mixed up with the deserving scholars and you’ll just have to go. Anyway, he hasn’t as yet and I have to say, it’s an awesome place.

So considering I’ve left the triathlons to my much fitter sisters and there’s only so many re-runs of Jeremy Clarkson that a person can watch without wanting to harm the Hammond guy – what did I find of interest today? Well now, seen as you asked, this morning a study was published in the British Medical Journal (BMJ) entitled ‘Suicidality and aggression during antidepressant treatment: systematic review and meta-analyses based on clinical study reports’ (Sharma et al., 2016). The objective of the study was to study serious harms associated with selective serotonin and serotonin-norepinephrine reuptake inhibitors (SSRIs and SNRIs). Now, as I can feel your eyes glazing over (just as mine did), there’s an article in the Telegraph that provides a simplified account of the study findings – an article which incidentally gives a well-deserved mention to my lovely friend Mr AntiDepAware.

Excerpt from the Telegraph article ..

Antidepressants can raise the risk of suicide, the biggest ever review has found, as pharmaceutical companies were accused of failing to report side-effects and even deaths linked to the drugs. An analysis of 70 trials of the most common antidepressants – involving more than 18,000 people – found they doubled the risk of suicide and aggressive behaviour in under 18s. Although a similarly stark link was not seen in adults, the authors said misreporting of trial data could have led to a serious under-estimation of the harms.”

While the study found no increased risk in adults, the Telegraph provides a quote from Professor Peter Gøtzsche, lead author of the study, who said “What I get out of this colossal underreporting of suicides is that SSRIs likely increase suicides in all ages”.

In a related BMJ editorial today, psychiatrist and author Joanna Moncrieff expressed concerns that many adverse events are being misrepresented – Several deaths were misclassified, and more than half the instances of suicide attempts and suicidal ideation were coded as ‘emotional lability’ or ‘worsening of depression’.

There are two hugely important findings in this study.

  1. the safety of Fluoxetine (Prozac), psychiatry’s main drug of choice for children suffering with mental trauma, was widely misrepresented by Lilly.
  2. antidepressants double the risk of suicidality and aggression in children and adolescents.

The study authors recommend – minimal use of antidepressants in children, adolescents, and young adults, as the serious harms seem to be greater, and as their effect seems to be below what is clinically relevant.

Considering Lilly’s consistent hiding of the harms of Fluoxetine and the recent inquests in the Dublin Coroner’s Court where this drug was implicated, access to the data is crucial in order to stop further unnecessary deaths. A mammoth task but not an impossible one, as shown recently by Le Noury et al (with Paroxetine and Study 329). My brain is frying at the thought of it; although a PharmaHealyGotzsche triathlon actually sounds quite fun.

.

Telegraph Article.

SHARMA, T., GUSKI, L. S., FREUND, N. & GØTZSCHE, P. C. 2016. Suicidality and aggression during antidepressant treatment: systematic review and meta-analyses based on clinical study reports. BMJ, 352.

LE NOURY, J., NARDO, J. M., HEALY, D., JUREIDINI, J., RAVEN, M., TUFANARU, C. & ABI-JAOUDE, E. 2015. Restoring Study 329: efficacy and harms of paroxetine and imipramine in treatment of major depression in adolescence. BMJ, 351.

cipramil (celexa) stories,, Random

Same dangerous drugs, different warnings!

FDA

Antidepressant drugs come with different warnings in Ireland and the US. In the US these drugs come with a black-box warning due to the increased risk of dangerous adverse effects, including suicide. In my opinion, the difference between the Irish Patient Information Leaflet (PIL) and the American PIL is criminal. The failure to warn here is negligent; don’t be another statistic, make an informed decision.

Here’s a quote from an article in the Irish Times in Oct 2009. The article concerns Shane’s case and our ‘allegation’ on RTE that antidepressants can cause suicide and homicide. Justin Brophy, president of the Irish College of Psychiatry, stuck his oar in: Some people believe doctors and the pharmaceutical companies work hand-in-glove to suppress the evidence. Says Dr Brophy: “If there was any implication of concealment of the truth, the IMB would know it. The facts are very open and accessible. No one is trying to conceal anything. . . . To imply [we] are beholden to the pharmaceutical industry is a misrepresentation. We don’t prescribe based on any information from the pharmaceutical industry – we get it from the IMB.”  The article (or Justin Brophy) failed to mention that the IMB is almost fully funded by the pharmaceutical industry. Is this the reason for the discrepancies in the PILs Justin?

D Walsh and J BrophyInterestingly, this picture is from Irish Psychiatry’s Summer 2010 News Bulletin, which also refers to Shane’s case. The picture is of Justin Brophy with fellow Psychiatrist Dermot Walsh. Dr Walsh had this to say in the British Medical Journal (BMJ): “In the context of the current debate on the efficacy of antidepressants the following may be of interest. Ireland’s suicide rate has risen threefold since antidepressants became available with the greatest increase occurring following the introduction of the SSRIs.” Did you not read that Justin?

For the thousands of people on these mind altering drugs in Ireland, here are the PILs for the same drugs in Ireland and the US (Courtesy of the RxISK website and Medicines.ie):              

  US                                        Ireland

Citalopram:    Celexa                      Cipramil/Citalopram/Cipager

Sertraline:       Zoloft                        Lustral/Depreger

Paroxetine:     Paxil                         Seroxat

Fluoxetine:     Prozac                      Prozac/Gerozac/Affex

Escitalopram: Cipralex                  Lexapro  (Same product as Celexa/Cipramil)

Fluvoxamine: Luvox                      Flaverin

Venlafaxine:   Effexor                     Efexor/Venlofex

Duloxetine:     Cymbalta                Cymbalta/Yentreve

It is not recommended that anyone should stop taking these drugs without consulting a (good) doctor. The problem is the risk of suicide, violence, mania and worsening depression which can occur upon starting, discontinuing and dosage change (up or down). If required, information on withdrawal can be found here.

Antidepressants for takers.

Antidepressants for prescribers.

Abnormal hearth rhythms: Citalopram and Escitalopram warning.

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cipramil (celexa) stories,, lundbeck, Newspaper and internet articles, psychiatry, Random

Dr Terry Lynch “100 years of misinformation in Psychiatry”

It’s unusual, to say the least, that a doctor will speak out against psychiatry, especially in Ireland. The College of Psychiatry of Ireland, as previously seen with Shane’s Case here, are staunch defenders of their misinformation and equally staunch defenders of the medical model, antidepressants in particular. Apart from Prof Healy, there are very few Irish medical professionals who are willing to risk the wrath of Irish Psychiatry. There have been some notable exceptions; Irish Psychiatrist Pat Bracken wrote this paper recently “Psychiatric Power: A Personal View” by Pat Bracken. This paper questions, inter alia, psychiatry’s use of dubious drugs. In this paper Pat Bracken questions the power that psychiatry has in Ireland, stating: “the decision-making powers that are currently given to psychiatry cannot be justified on either scientific or moral grounds”.

Then there was the lovely Dr Corry RIP who died on 22/02/2010. He spoke out against antidepressants saying that these drugs could tip someone into suicidal and homicidal behaviour. Dr Corry who was speaking in defense of Shane and against SSRI’s, then became the subject of a medical council complaint initiated by Prof Timothy Dinan of University College Cork. Prof Dinan is an advocate for antidepressants and has worked as a speaker for a lot of pharmaceutical companies, including Lundbeck (the makers of Citalopram, the drug Shane was on). Here is Prof Dinan again, who will be speaking for Lundbeck at the Nov 2012 symposium in Barcelona. Link. Note the nice BIG Cipralex advertisment at the end of the programme.

Another Irish doctor who is becoming increasingly outspoken against the misinformation in mental health and psychiatry is Dr Terry Lynch. He is the author of two books: ‘Beyond Prozac’ and his latest one ‘Selfhood‘. Here he is speaking out against psychiatry on YouTube; It’s 13 minutes long and well worth a watch. I’d be careful if I was you Terry, you know Irish Psychiatry don’t like to be contradicted….

lundbeck, Newspaper and internet articles, Random

Oops…. Did pharma really say that?

Last week I came across this article on IrishHealth.com on depression where it states “It is believed that depression is linked to an imbalance of chemicals within the brain” and SNRI’s “work on both serotonin and noradrenaline to achieve a better balance of chemicals in the brain to alleviate depression”. The chemical imbalance theory again? No such thing has ever been proven!! There is no test, never has been, which can prove any chemical is related to depression. It was a theory which drug companies used (and gullible doctors copied) to persuade people that there was something inherently wrong with their brain.

……………..

Anyway, it made me think about the ridiculous things drug company representatives have said and subsequently been caught out. Here’s a selection….

(1) Pfizer, speaking of Celebrex: They swallowed our story, hook, line and sinker,” Link.

(2) Lundbeck, speaking of Indocin IV (used for treating premature babies): “We can price these almost anywhere we want given the product profiles”Link.

(3) Pfizer, speaking of Zoloft and Prozac: ‘Marketing are very aware that a patient on Zoloft involved in an incident of mass homicide could severly affect the image and commercial success of Zoloft’. “I do not think fluoxetine are ‘out of the woods’ as regards their association with violence/ suicidality.” Link.

(4) Eli-Lilly, Speaking of Prozac: “Anything that happens in the UK (England) can threaten this drug (Prozac) in the US and worldwide. We are now expending enormous efforts fending off attacks because of (1) relationship to murder and (2) inducing suicidal ideation.” Link.

(5) Eli-Lilly, Speaking of Prozac: “I do not think I could explain to the BGA, a judge, to a reporter or even to my family why we would do this especially on the sensitive issue of suicide and suicidal ideation.” Link.

(6) GSK, Speaking of Seroxat: “The evidence, however, is clear, these medicines are not linked with suicide, these medicines are not linked with an increased rate of self harm.” Of course that was before they had to admit that Seroxat actually could cause suicide Link.

(7) GSK, Again speaking of Seroxat: “I utterly refute any allegations we are sitting on data, that [we] have withheld data or anything like that.” That was before GSK were found guilty of hiding the data, including suicides, caused by Seroxat Link, and hiding the data which included heart risks and deaths caused by Avandia Link.

(8) GSK: ‘The vast majority of drugs – more than 90 per cent – only work in 30 to 50 per cent of the people, I wouldn’t say that most drugs don’t work. I would say that most drugs work in 30 to 50 per cent of people. Drugs out there on the market work, but they don’t work in everybody.” Link.

(9) Lundbeck, statement after Shane’s Inquest: “Extensive scientific studies have shown that there is no evidence linking citalopram to violent behaviour.” and “A review of all available data for citalopram (that from clinical trials and that collated after the medicine was made available) shows no increased risk of suicide.” Silly billies…They had forgotten about writing this letter to the Canadians warning of ‘self harm and harm to others’, Link

GSK’s stupid statements came courtesy of ‘Seroxat sufferers stand up and be counted’ Here. He actually gave me a page-load but I decided to keep it short!

cipramil (celexa) stories,, lundbeck, Newspaper and internet articles

Citalopram Song…this one’s for you Lundbeck!

I can’t remember if I put this song up before but this guy tells his story very well. He obviously felt strongly enough to write about his experience on Citalopram. It’s actually quite catchy although it does make me feel sick listening to it. At least he’s still alive to sing it. Not everyone is lucky enough to survive Citalopram!

The Wombats: Link to story behind his song here.

Lyrics below…

Anti-D

Please allow me to be your anti-depressant
I too am prescribed as freely as any decongestant

We kick back and let the pills do the talking
People hear a distinct rattle when we’re walking
Then there’s the extra two stone that’s our only guarantee

Our vivid dreams are just like big production movies
They get entangled well within our daily routines
So please re-think or use my trademark strategy

And please allow me to be your anti-depressant
I too am prescribed as freely as any decongestant

It’s hard to smile when you’re as flattened as a pancake
The only tears come from our heads when we concentrate
Perhaps I’m being unjust or perhaps you agree

Still I’ve thrown away my citalopram
I needed more than what was in those 40 milligrams
So cast away with the doctor’s plans

And please allow me to be your anti-depressant
I too am prescribed as freely as any decongestant

Still I’ve thrown away my citalopram
Although I felt as grim as the reaper man
So cast away with the doctor’s plans
Like me

“Anti-D” as written by Matthew Edward Murphy, Daniel Joseph Haggis, Tord Oeverland Knudsen
Lyrics © Warner/Chappell Music, Inc.
Lyrics powerd by LyricFind
Read more at http://www.songmeanings.net/songs/view/3530822107858861235/#hKZaC5DoovgWw2Kr.99

cipramil (celexa) stories,, lundbeck, Newspaper and internet articles, psychiatry

Is Harry Aware?

One of Ireland’s ‘Mental Health Charities’ which has a long association with Lundbeck is ‘Aware’. As I said in my last post, why would a mental health charity associate itself with a pharmaceutical company that make antidepressants, which (by their own admission) can cause a person to enact suicide. Major conflict of interest, I think.

Dr Harry Barry is a board member of Aware and is a medical doctor based in County Louth. According to the synopsis of his book here,he has a particular interest in the area of mental health and has extensive experience in his practice of dealing with issues such as depression, addiction and anxiety. He regularly features on national radio and in national print to discuss mental health issues, including Today FM and The Irish Independent.”

In one of these Irish Independent articles, Dr Barry makes this statement, supporting Lundbeck’s Lexapro, he said “Common anti-depressants in 1990s were Prozac, he says. Now Lexapro, which he describes as a more modern and powerful form of Prozac, is more commonly prescribed.” That sure is a good enticement for someone to try Lexapro. The only problem I have with Harry’s statement is that it is wrong.

Considering I’m not a medical professional, I asked Professor David Healy, who is probably the best person in the world to ask about Ssri’s, what he thought about Dr. Barry’s statement. He said, and I quote “This is wrong on a few fronts, citalopram – same as lexapro – was first made before prozac. Citalopram/Lexapro is not more powerful and may even be weaker than Prozac”.

At the launch of Lundbeck’s Mental Health Barometer, Dr Barry says ““When you take anti-depressants, they work from the bottom of the brain up. When you engage in talk therapy, it works from the front of the brain down. However, the studies have shown that when you use the two approaches together, the results are more effective and quicker to get a result.” I thought this was codswallop, so I asked Professor Healy what he thought about the latter statement; He said one word: baloney.

Some questions need to be asked. If the Irish public are getting their Information from the National papers, surely on such important issues, the relevant information should be based on scientific fact?

Newspaper and internet articles, Random

Prozac led to grandfather’s suicide.

Prescription pills led to Littlehampton grandfather’s suicide  

Brian Palmer, 63, another SSRI victim.

Here’s another Coroner’s warning concerning another SSRI, Fluoxetine, also know as Prozac, and again the Coroner is left to do the job of the medicines regulator. Days after he began taking Prozac, Brian Palmer’s mental health deteriorated and he shot himself in the head.

Excerpts from Article…

THE devastated family of a grandfather who killed himself following a bad reaction to anti-depressants have urged doctors to warn patients of the possible side-effects before prescribing the drugs.

The coroner at an inquest held last Wednesday (March 14) at Chichester concluded he took his own life following the prescription of anti-depressant pills.

Speaking after the hearing, Brian’s widow Jennifer, 62, appealed to doctors to take the time to explain to their patients all the possible side-effects of any drugs they prescribe.

She said: “I noticed a change in him almost straight after taking the pills. I asked to see the box in the days before but he said he couldn’t find it. I found it a few days after his death and it listed all the changes I had seen in him. My heart just stopped.

The inquest heard how, days after Mr Palmer began taking the drugs, his mental health deteriorated.

Recording a narrative verdict, coroner Penelope Schofield said: “He took his own life following the prescription of the drug Fluoxetine and Zopiclone.”

The coroner said she would be writing to the Fitzalan Medical Centre to advise GPs there  to warn all patients of the potential side-effects any prescribed drug can have. Full Article.

……………………………………………………………..

How much evidence is needed? There is so much evidence that Prozac and other SSRI’s can cause suicide and homicide and yet this poor man probably had no warning. At least in England, unlike in Ireland, there was no psychiatrist attending this Inquest denying that SSRI’s can cause suicide.

The first high-profile Prozac Murder/suicide; Link.

Prozac blamed for woman’s suicide; Link.

John virapen admits to bribing the Swedish Government to enable the licencing of Prozac; Link.

Then there is Maria, whose son died by by suicide less than 2 weeks after starting Prozac; Link.

Prozac defence for murder; Link.

Newspaper and internet articles, psychiatry, Random, Shanes story.

Another Irish Doctor willing to speak out about the dangers of Anti-depressants

Another Irish Doctor willing to speak out about the dangers of Anti-depressants. In today’s Irish Examiner another doctor states his opinion, contradicting the stance of the Irish College of Psychiatry; Respect to Doctor Gascoigne. The picture, by the way, is one of Shane’s that he took in Berlin on a College trip; I thought it was suitably apt.

 

Anti-depressants’ effects must be known

 Friday, March 09, 2012

In your excellent coverage of the recent comments by former deputy state pathologist Dr Gilsenan of a connection between anti-depressants and an increased risk of suicide, The College of Psychiatry of Ireland states “… there is no evidence anti-depressants can cause harm”.

It might be good if the college consults the information supplied by the pharmaceutical company which manufactures Prozac, a commonly prescribed antidepressant. It is clearly stated that Prozac can cause agitation, panic attacks, aggressiveness, impulsiveness, irritability, hostility as well as suicidal thoughts or attempts.

As a minimum, it is important that anyone prescribed an anti-depressant should be fully informed of possible adverse effects, it should only be prescribed as part of a recovery plan with appropriate psychological support and people must be monitored regularly.

Dr Stephen Gascoigne
Market Quay
Bandon
Co Cork

http://www.irishexaminer.com/opinion/letters/anti-depressants-effects-must-be-known-186502.html

Cases, Newspaper and internet articles, Our story., Shanes story.

Why did the Irish Government not warn of the dangers of SSRIs?

The issue of ssri’s and their causal link to suicide has been around for many years and will be around for many more, as more and more suicides and murder/suicides are found to be caused by antidepressants. This month in another landmark ruling, a Canadian Judge held that Prozac Was To Blame for Murder. He was ruling on the case of a teenager who inexplicably murdered his friend while on Prozac. Judge Heinrichs said: “(Prozac) clearly affected his behaviour in an alarming way. He was simply not the same person[1].”

Years before Shane took an ssri, which resulted in the tragic consequences of 2009, the Irish Government was made aware of the dangers of antidepressants. Unfortunately for my family and another, nothing was done! A detailed report was compiled for the Oireachtas by Nuria O’Mahony and Mindfreedom Ireland, with the help of Dr. Michael Corry, detailing the corruption by the pharmaceutical industry in Ireland and their manipulation of data from clinical trials[2]. Not only that, but it delves into one particular company, GSK, and their now-proven concealing of the dangers of Seroxat/Paxil, particularly in regard to stimulation and its adverse consequences of murder and suicide.

The fact is, the pharmaceutical industry giants –with tacit complicity by the government oversight regulatory body that has lost its way- are able to CONCEAL the most damaging facts about the products the IMB approves for wide marketing without so much as FULL disclosure of the hazardous risks. Only the court provide a mechanism for getting at the truth, even though current laws allow defendant companies to keep documents sealed. It is strictly in the PUBLIC INTEREST to CHANGE THE LAW and open the documents to public scrutiny. By sealing relevant documents, a symbiotic relationship is formed: companies can CONTINUE to engage in fraudulent marketing resulting in PREVENTABLE HUMAN TRAGEDIES, and  lawyers can get rich by suing multiple times for the same violations”.

Before this report, in 2003, Professor Healy spoke at the Irish College of Psychiatry’s AGM in a debate entitled…”This house believes there is a causal link between suicide and selective serotonin re-uptake inhibitors (SSRIs)”. Professor Healy, spoke in favour of the motion. Prof Patricia Casey and Prof Kevin Malone, both of the department of psychiatry at University College Dublin, opposed the motion[3].

In a later lecture at Columbia University, Prof. Healy had this to say, which I presume was referring to that debate… It has in fact been very difficult to get issues of suicidality and psychotropic drugs debated in academic forums. In one of the few such forums, at an Irish College of Psychiatrists meeting in 2003, my understanding is that many clinicians and academics in the audience were briefed by individuals linked to Pfizer and GlaxoSmithKline on issues to raise with Healy[4].

So, in my opinion, there is absolutely no excuse or reason, for our Government or medical professionals to say they were unaware or not sufficiently warned, of “any issues concerning these drugs”. I am also personally aware, long before 2009 that one particular consumer went to the Health minister and spoke for hours (in the Dail) on the terrible effects that an ssri had on him, rendering him suicidal and extremely violent. Extensive notes were taken at this meeting, so are these files gathering dust or were they forwarded to the IMB?

The useless Irish Medicines Board (IMB) are almost fully funded by the pharmaceutical industry, the current CEO having previously worked for pharma, members of their advisory committee having received honoraria (payment) from multiple pharmaceutical companies,  and nobody sees this as a conflict of interest?

And why did the Irish Government do nothing to warn Irish consumers? The Oireachtas report states that Ireland is the biggest pharmaceutical exporter in the world, so are we back to the Haughey era of brown envelopes? Just how desperate are the Irish Government to keep these pharmaceutical companies happy?

References,


[1] PRWeb, http://www.prweb.com/releases/2011/11/prweb8941528.htm

[2] Executive Report for the Oireachtas Subcommittee for Health, Link.

 [3] The Irish Times, 29/03/2003, http://www.highbeam.com/doc/1P2-24668808.html

 [4] Joint Program at Rutgers University and Columbia University, School of Public Health, http://www.ahrp.org/COI/HealyColumbia1005/index.php

cipramil (celexa) stories,, lundbeck, Newspaper and internet articles

Are antidepressants the cause of the recent spate of murder/suicides in China? 抗抑鬱藥,最近接連發生在中國的謀殺 /自殺的原因?

抗抑鬱藥,最近接連發生在中國的謀殺 /自殺的原因?

Are antidepressants the cause of the latest spate of murder/suicides in China?

In the last year there has been a series of newspaper articles concerning recent murder/suicides in China. It seems that this kind of tragedy was virtually unheard of in China until recently. China is relatively new to the antidepressant market, I wouldn’t be too sure that the Chinese are aware of the dangers; I’m sure the various drug companies are not volunteering the information that these drugs can actually cause both suicide and homicide.

As you my be aware, my son killed himself and another young man in Aug 2009. I have the expert report which Professor Healy did for Shane’s Inquest, stating that, in his opinion, this was caused by Cipramil. For anyone that wants to read his report, I have blanked out the names of the other people involved but will attach it here…Professor Healy’s Report March 2010.

Back to China…

School attacks in the People’s Republic of ChinaWikipedia

A series of uncoordinated mass stabbings, hammer attacks, and cleaver attacks in the People’s Republic of China began in March 2010. The spate of attacks left at least 21 dead and some 90 injured.

Kindergarten killings are a turning point for ChinaThe Telegraph

The series of kindergarten murders that has swept across China marks a turning point for Chinese society.

In a country which reveres children – especially since the one-child policy was introduced in the late 1970s – it is difficult to imagine how any atrocity could be worse than the premeditated murder of innocent toddlers. Since March 23, when a mentally-unstable doctor stabbed eight primary school children to death, each copycat attack has added to parents’ fears.

Life on the margins of Chinese society has always been unfair and difficult, but it is near impossible to imagine the rage that must have driven these men to slit the throats of young children. Clearly, something is very rotten in China.

Exactly what is going on in China?? The Moderator

Exactly what is going on in China?

A rash of bloody, knife and meat cleaver murders of small school kids by adults have stunned China, a country where children are treasured. It seemingly matches the inexpicable killing sprees that peppered American history over the past few decades. The question is “why.” And the answer so far is: “no one knows” — but a lot of parents now fear.

……………………..

The most widely-used antidepressants in China by the end of last year were GlaxoSmithKline’s Paxil/Seroxat (paroxetine) with a value market share of 18%, followed by Pfizer’s Zoloft (sertraline; 10%) and Eli Lilly’s Prozac (fluoxetine; also 10%). Lundbeck’s older drug Cipramil (citalopram), also sold by Xian-Janssen, and Lexapro had market shares of 6.5% and 3.0% respectively.

Soo,  the Chinese people have been introduced to Seroxat, Prozac, Zoloft, Cipramil and Lexapro which can cause suicide and homicide ideation and there has been a spate of murder/suicides. Now isn’t that a co-incidence.

Has it anything to do with Lundbeck’s recent marketing push on Lexapro in China?

Lundbeck to establish a strong, dedicated sales… FE Investegate

Lundbeck will substantially increase sales and marketing efforts behind Lexapro in China. Lundbeck already has a foothold in China and stands to benefit from the rapidly evolving Chinese CNS market.

Lundbeck sees China as land of opportunity for Lexapro…PharmaTimesOnline

Lundbeck has unveiled plans to double its sales force in China with a specific emphasis on promoting the blockbuster Lexapro in the growing antidepressant market there.

So it begs the question, considering all of the above drugs can cause suicide and homicide, how many of the perpetrators were on an antidepressant?

One worrying aspect is that Lundbeck have just launched Lexapro in Japan. So it remains to be seen if the next headlines will be “School attacks in Japan” and “Exactly what is going on in Japan”?

GSK have already trialed the notorious Seroxat on Japanese  7-17 year olds, despite the fact that ssri’s have been proven to be detrimental to children, even causing deaths. But then, what do you expect from a company with such dubious ethics (on an equal par with Lundbeck) who see no moral issue with doing drug trials on children as young as 7?  Link.