Random

GSK: Glaxo, Study 329 and Keller..

Study 329

                                                        Study 329.

Let me explain a little about Study 329. This was a study done in the 90s to study the efficacy of paroxetine (aka Paxil/Seroxat) in teenagers. The study was conducted by Professor Martin Keller (et al) of Brown University and funded by GlaxoSmithKline (GSK, makers of Paroxetine). The findings that Paroxetine was ‘safe and effective for adolescents’ led to the widespread medicating of children with Paroxetine and other Selective Serotonin ReUptake Inhibitors (SSRIs).

What surfaced later was that the study was in fact ghostwritten by a PR company for GSK and that far from being ‘well tolerated’ in children, Paroxetine actually caused children to become suicidal – a matter which was hidden by the drug company. If the SSRI era will stand as one of the most shameful in the history of medicine (David Healy), then Study 329 will as stand the most shameful in the history of Brown University and evidenced based medicine. The integrity of medical professionals and medical journals who publish ghostwritten articles that subsequently causes harm (in this case to children) must also be called into question. According to Shelly Jofre of the BBC, in one year alone, the lead author, Professor Keller, earned half a million dollars from drug companies, including GSK.

It’s interesting to note that the journal in question, The Journal of the American Academy of Child and Adolescent Psychiatry, has consistently refused to retract the study. Furthermore, Brown University, despite huge controversy (and huge fines for GSK), has refused to reconsider its position and back a retraction. GSK’s fraudulent marketing of Paroxetine (and other drugs) led to the largest health care fraud settlement in U.S. history – 3 billion dollars.

I wrote to the President of Brown University, Christina Paxson (in 2013), regarding the University’s inaction with Study 329. She replied:

“As you note, there have been questions raised about Study 329 for a number of years.  The U.S. Justice Department’s settlement with GlaxoSmithKline and, most recently, the decision by the editors of the Journal of the American Academy of Child and Adolescent Psychiatry not to retract the original paper have brought it back into the news. Brown University takes allegations of research misconduct very seriously.  Research integrity is a core value for Brown, and the University has put in place policies and procedures that respond forthrightly to any credible allegation of impropriety.  These policies and procedures support thorough and impartial reviews as warranted while preserving confidentiality for all participants.  I realize that the University’s concern for the integrity and confidentiality of the process can be misconstrued as inactivity.  I am satisfied that the University does not hesitate to take action when warranted.”

Hmm..

So there you have it – a little background into Study 329. So why bring it up now?

Study 329 has been re-written by a team of independent experts, including David Healy and Micky Nardo (aka 1boringoldman) et al. Having spent years trawling through the data of the original study, they have now rewritten its true findings. Yesterday, in what was a momentous occasion for parents who have lost a child to Paroxetine, the British Medical Journal (BMJ) published Restoring Study 329: efficacy and harms of paroxetine and imipramine in treatment of major depression in adolescence’. 

You will be shocked to note that GSK intentionally hid the hugely increased risk of suicidality in children, subsequently causing many deaths. The re-analysed trial found that Paroxetine “is neither safe nor effective for adolescents with depression”; that at least 12 out of 93 children taking the drug had developed suicidal thoughts (Reuters); with one child being admitted due to severe suicidal and homicidal ideation towards his parents (New York Times).

I don’t like using bad language, or to be more truthful, my mother doesn’t like it (I know, I know, I’m feckin 50), yet occasionally nothing else will suffice. GSK, the absolute sociopathic ba**ards, put childrens’ lives at risk, causing many to kill themselves and leaving their parents to endure a pain and grief that no human being should ever have to suffer – for profit. Furthermore, Brown University has actively allowed this situation to continue rather than admit it was wrong. Shame on all concerned.

For more information see Restoring Study 329, Davidhealy.org and 1boringoldman.

See also GSK‘s mission statement.. ‘to help people to do more, feel better, live longer’. For the sake of my poor mother – no further comment!

Cases

The ‘Beast of Baflo’ or a case of GSK (Glaxo’s Seroxat Kills)

Baflo policeA case presently being played out in a Netherlands Court involves a man who killed two people: his girlfriend, and a policeman who was responding to the emergency call.

Mr Asalam S. was taking Paroxetine (AKA Paxil and Seroxat) at the time of the killings. He is originally from Benin in Africa and at the time of the killings (April 2011), he had recently had his asylum application refused. The incident occured in the village of Baflo, which led to the perpetrator being dubbed as ‘The Beast of Baflo’. The trial continues in the Groningen courts tomorrow (Monday 11 Feb).

Last week, testimony regarding the dangers of anti-depressants was offered to the court by professor of pharmacology Dr. Anton Loonen. Prof/Dr. Loonen from the University of Gronengen, stated that this drug can lead to violent outbursts. The newspaper reported that Mr Asalam S. told his doctor that he was feeling unwell, which subsequently led to his dosage of Paroxetine being increased. As we know this can lead to tragic consequences. According to statements made by officers he acted ‘like a zombie’ and someone who ‘had nothing to lose’.

No doubt GlaxoSmithKline will have their ‘experts’ attending. It’s unfortunate for them that they have a dubious history; what telling the truth means to GSK, means something entirely different to the general public!  This pharma company (GSK) were previously held liable in the case of Donald Schell, 60, who had been taking Paxil for just 48 hours when he shot and killed his wife, his daughter, his granddaughter and himself. You can download a copy of the verdict here.

This is not the first time that the Netherlands have come across an alleged ‘Seroxat induced’ killing. There was the so-called ‘axe murders’ which happened in Badhoevedorp in 2008. A former flight attendant Elzelien K. (aged 66) killed her husband, 61, and daughter, 22, as they slept. She had been  ‘depressed’ since her son had died in an accident 10 years beforehand but had recently started on a high dosage of Seroxat. During the trial, Elzelien K. said her actions were an ‘unimaginable mystery’ and ‘they were everything to me’. Dutch article here.

In a recent post Professor Healy stated that the information about SSRI induced disinhibition, violence and suicide has been in the public domain for nearly 25 years. He also stated:

“Somewhere around 90% of the school or other mass shootings that have happened in recent years in America or Europe have involved shooters on psychotropic drugs usually antidepressants. The public sympathy for the victims typically also extends to the doctor who is seen as one more victim.  But the so called perpetrator is much more likely to be a victim than the doctor.  He may have been turned into a guided missile by his doctor.  These are people in treatment whose doctors clearly failed to recognize the risks they posed.”

So as more and more experts warn of the dangers of SSRIs, the inaction by the the EU is increasingly baffling. Of course, it’s not just Seroxat which has the potential for suicide and homicide. All SSRIs can cause suicide, violence. akathisia, worsening depression, ect, ect. Five days after first taking Celexa, Robert Raines, 78, shot and killed his wife, Elsie, 71, then himself. Article here. These cases will go on and on until something is done to hold the different pharmaceutical companies responsible.

It will certainly be interesting to see what happens in the Groningen courtroom. No doubt the pharma experts muppets will tow the company line. What is Glaxo’s motto? Oh yes; “enabling people to do more, feel better and live longer”. Tell that to the Seroxat victims!

Many thanks to Noel McCullagh, an Irish journalist living in the Netherlands, for the translating/reporting of this story.

cipramil (celexa) stories,, Random

Same dangerous drugs, different warnings!

FDA

Antidepressant drugs come with different warnings in Ireland and the US. In the US these drugs come with a black-box warning due to the increased risk of dangerous adverse effects, including suicide. In my opinion, the difference between the Irish Patient Information Leaflet (PIL) and the American PIL is criminal. The failure to warn here is negligent; don’t be another statistic, make an informed decision.

Here’s a quote from an article in the Irish Times in Oct 2009. The article concerns Shane’s case and our ‘allegation’ on RTE that antidepressants can cause suicide and homicide. Justin Brophy, president of the Irish College of Psychiatry, stuck his oar in: Some people believe doctors and the pharmaceutical companies work hand-in-glove to suppress the evidence. Says Dr Brophy: “If there was any implication of concealment of the truth, the IMB would know it. The facts are very open and accessible. No one is trying to conceal anything. . . . To imply [we] are beholden to the pharmaceutical industry is a misrepresentation. We don’t prescribe based on any information from the pharmaceutical industry – we get it from the IMB.”  The article (or Justin Brophy) failed to mention that the IMB is almost fully funded by the pharmaceutical industry. Is this the reason for the discrepancies in the PILs Justin?

D Walsh and J BrophyInterestingly, this picture is from Irish Psychiatry’s Summer 2010 News Bulletin, which also refers to Shane’s case. The picture is of Justin Brophy with fellow Psychiatrist Dermot Walsh. Dr Walsh had this to say in the British Medical Journal (BMJ): “In the context of the current debate on the efficacy of antidepressants the following may be of interest. Ireland’s suicide rate has risen threefold since antidepressants became available with the greatest increase occurring following the introduction of the SSRIs.” Did you not read that Justin?

For the thousands of people on these mind altering drugs in Ireland, here are the PILs for the same drugs in Ireland and the US (Courtesy of the RxISK website and Medicines.ie):              

  US                                        Ireland

Citalopram:    Celexa                      Cipramil/Citalopram/Cipager

Sertraline:       Zoloft                        Lustral/Depreger

Paroxetine:     Paxil                         Seroxat

Fluoxetine:     Prozac                      Prozac/Gerozac/Affex

Escitalopram: Cipralex                  Lexapro  (Same product as Celexa/Cipramil)

Fluvoxamine: Luvox                      Flaverin

Venlafaxine:   Effexor                     Efexor/Venlofex

Duloxetine:     Cymbalta                Cymbalta/Yentreve

It is not recommended that anyone should stop taking these drugs without consulting a (good) doctor. The problem is the risk of suicide, violence, mania and worsening depression which can occur upon starting, discontinuing and dosage change (up or down). If required, information on withdrawal can be found here.

Antidepressants for takers.

Antidepressants for prescribers.

Abnormal hearth rhythms: Citalopram and Escitalopram warning.

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Newspaper and internet articles, psychiatry, Random

Professor David Healy: Time to abandon evidence based medicine?

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A talk by Prof David Healy from the Institute of Psychological Medicine and Clinical Neurosciences at Cardiff University. The talk was presented at the Cardiff University School of Psychology on 26th November 2012.

Prof Healy makes an interesting point about Sertraline/Zoloft (the drug that Anna Byrne was prescribed in her pregnancy) at 9.40 mins and 48 mins. 80% of Sertraline trials proved negative and yet Sertraline was approved long before it was prescribed to Anna and Nicolas Maguire. So terribly tragic, so very wrong and so avoidable. An article in the Irish Independent regarding Anna’s death stated “Mrs Byrne’s GP had started her on Sertraline – an anti-depressant regularly used during pregnancy – and Dr Sheehan doubled her dosage….” This is the same dangerous drug that the NIMH deem fit to be trialed in children as young as seven…Link.

Anway, for those of you with an attention span like mine, I’ve gone through the video and put the time to the important bits:

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Ghostwriting at 4 mins

Study 329 at 5.30 mins & 10.45 mins

Pfizer’s Zoloft/Sertraline worst antidepressant (80% of trials proved negative) at 9.40 mins and 48 mins

The truth behind GlaxoSmithKline’s proposal to make data available at 24.30 mins

‘It’s the disease, not the drug’. Heard that one before anyone? at 38 mins

For the seriously depressed, Antidepressants don’t work at 38.10 mins

GSK Seroxat suicide; the way around the problem of Paroxetine/ Paxil/ Seroxat causing suicide at 42.30 mins

Antidepressants in pregnancy at 51.10 mins

Sex in a spray at 51.40 mins

(Shocking) Sacked for not taking flu-vaccine at 54.35 mins

Discussion at 58.12 mins

Weight-gain on Zyprexa at 59 mins

ECT at 62.19

Newspaper and internet articles, psychiatry, Random

Was Anna Byrne another Sertraline (Zoloft) victim?

There is a very public debate raging in Ireland at the moment regarding the tragic death of a young woman who died while suffering a miscarriage at Galway University Hospital. An estimated two thousand people protested outside Leinster House (Irish Parliment) in memory of Savita Halappanavar, who died of septicaemia as a consequence of the Irish Government’s reluctance/cowardice to legislate in this area. My heart goes out to her family and indeed to the woman and her child. The country is in uproar and rightly so.

There was another young woman who also died this year (March) but on this occasion there was no public outcry or no protest outside Leinster House (Irish Parliment). Anna Byrne was Carrying twins (almost full term) when she died by jumping off Howth head. Her inquest was held last week and was reported in the Irish independent (among other more sensationalist newspapers). Given the sensitivities surrounding this case and the fact that the family are (and will always be) grieving, I debated long and hard about writing about Anna. I was away with my family in Berlin when this report came out and Anna was never far from my thoughts; she and her two sons deserved more.

The really surprising thing was that the ‘Independent’ reported on the details of this unfortunate woman’s treatment. She was being treated by her doctor and subsequently a psychiatrist. Irish media, in cases where a person has died by suicide (unlike the UK and the US) rarely report on a person’s Inquest due to the fear of ‘copycat suicides’ and ‘social contagion’. There are strict media guidelines with the reporting of these cases; how’s that working in Ireland you might ask? Not too good!

Anna Byrne who was 35 and heavily pregnant with twins, had been on Seroxat for a number of years. This drug was discontinued earlier in her pregnancy. She was then put on Sertraline by her GP who described it as a commonly used antidepressant during pregnancy; seriously? Sertraline aka Lustral (Ireland) and Zoloft (US) commonly prescribed during pregnancy? Did this doctor not know of the birth defects associated with this family of drugs? Was this woman warned that this drug can cause suicide, depression, aggression, manic behaviour and serious birth defects? Adam Urato, assistant professor of maternal-fetal medicine at Tufts University School of Medicine and a co-author of a recent paper on this very issue, said:

“The truth of the matter is that we are currently witnessing a large-scale human experiment. Never before in human history have we chemically altered human foetal development on such a large scale… As I am telling you this right now, there is a doctor somewhere in the world counselling a pregnant woman that if she stays on her antidepressant medication she will help control her mood and that will lead to a better pregnancy result – and there really is not a shred of evidence to support that.”

Was Anna told that these drugs can, at the very least, double the suicide risk? Was she told that the  danger period is upon starting, discontinuing, or changing dosage (up or down)? This woman’s dose was doubled 6 days before her death by psychiatrist John Sheehan. C’mon, join the dots here. Does this woman and her two children not deserve every woman in this country to protest outside government buildings?

I looked up the psychiatrist ‘Dr John Sheehan’ and found him here, speaking at a conference supported by Pfizer (makers of Sertraline/Zoloft), Eli Lilly and Jansen. The speakers also included Timothy Dinan of UCC who last year denied any knowledge that Zoloft can cause suicide following Nicolas Maguire’s inquest in May 2011. Mr Maguire died by suicide shortly after being prescribed Zoloft for anxiety. Similar to most psychiatrists and medical professionals who publicly deny problems with these drugs, Timothy does a lot of work for pharmaceutical companies. This, unlike in the US, is not seen as a serious conflict of interest.

The body entrusted with the expertise in this area ‘The Irish College of Psychiatry’ (who have collectively denied that antidepressants can cause suicide) will defend their ‘medical model/drugs’ till the end, as in the recent debate with Professor Healy and Professor Veronica O’ Keane here. They will spout that the ‘benefits outweigh the risks’ till they actually convince themselves. This is despite the EMA warnings and despite the fact that the drug companies have admitted that the drugs can cause suicide. Notice the difference in Zoloft’s Patient Information Leaflet from Ireland and the US; Criminal.

I would remind medical professions that they are walking on thin ice, as was shown in the the case of Dunne (an inf.) v. National Maternity Hospital [1989] IR 91. Here it was found:

“A medical practitioner who establishes that he followed a practice which was general and approved by his colleagues of similar specialisation and skill is nevertheless negligent if the plaintiff thereupon establishes that such practice has inherent defects which ought to be obvious to any person giving the matter due consideration.”

Given that ex-Seroxat users have declared that the adverse discontuation effects can last for months and sometimes years, the introduction of Sertraline and the subsequent doubling of dosage can all cause a person to act on suicide ideation, it is entirely plausible that the medication caused Anna and her babies’ deaths. Considering Anna is dead, the benefits did not outweigh the risks in this case.

Where is the public outcry for Anna and her babies? The Irish Government have been informed by Professor David Healy that these drugs are causing suicide, that these drugs are the leading cause of death within the mental health field and that the same drugs are causing misciarrages and birth defects. At the same meeting Dr Declan Gilsenan said he had serious concerns that more people are taking their own lives as a direct result of seeking help (and subsequently prescribed mind altering drugs), than those who have not. The Government’s inaction on this issue is a bloody disgrace!

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UPDATE REGARDING SEROXAT; Syracuse, N.Y. — Joe Mazella, Basketball coach, died by suicide in Sept 09 while on Seroxat. His widow, Janice Mazella has just won a $1.6 million medical malpractice verdict on Tuesday Nov. 20, 2012 against two psychiatrists who had treated the coach before he committed suicide. Here.

https://leoniefennell.wordpress.com/2012/05/03/the-medical-experts-meet-in-leinster-house/

http://www.theaustralian.com.au/news/world/new-drug-fears-for-pregnant-women/story-fnb64oi6-1226503730380

cipramil (celexa) stories,, lundbeck, Newspaper and internet articles, Our story., psychiatry, Random, Shanes story.

Are they mad or what?

I have written an article which appears in the ‘health and living’ section of the Irish Independent today; here.

The writing is all mine this time, so for anyone who doesn’t agree; it’s all my work and I stand by everything I said. There was a paragraph missing to do with antidepressants and miscarriages; I feel this is very important so I’ve left it in here. All stats were verified by Prof David Healy.

Are they mad or what? 
The Irish Independent have asked me to write this article; are they mad or what? ‘Mad’ is a word I am well used to hearing. Having lost my son in the ‘most’ tragic circumstances in 2009, I’m left as most mothers with a dead child are left: in cloud cuckoo land, extremely sad and just a little bit mad. In my case I’d say ‘more than a little mad’ but I don’t want to tar every bereaved mother with my madness brush. What is it with Irish people and their reluctance to talk about death and dead people? I have never heard so many people talk about the ‘dreadful’ weather; whatever you do, don’t mention that big fat elephant in the room. Most of the time I couldn’t tell you what day of the week it is, never mind what the ‘dreadful’ weather is like, but please feel free to talk about that big fat grey thing with the huge trunk; my son. He’s dead, not erased from existence, but don’t upset the ‘mad’ bereaved woman whatever you do! Say the wrong thing, by all means, but don’t pretend he didn’t exist and talk about the ‘dreadful’ weather! I can’t tell you how close some people have come to manual strangulation, simply by saying ‘it’s a lovely day’ or more likely ‘the weather’s terrible, isn’t it?’
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Before I get shot down for using the ‘m’ word, I’d like to say that the so-called ‘mad’ people that I’ve met in the last three years are no madder than most of you, and definitely not I. Some of these people have been told that they have a ‘chemical imbalance’ of the brain; so in order to keep their brain functioning as it’s supposed to, they will need to stay on medication for the rest of their lives. These mad dysfunctional lot could teach the so-called ‘normal’ society a thing or two; mainly about kindness, compassion and a willingness to help others. They are also the ones who are shouting from the rooftops that the chemical imbalance theory is just that; a theory. For decades we were led to believe that depression was caused by low serotonin levels in the brain. There is no way, never has been, to measure serotonin in a person’s brain, and absolutely no evidence that low serotonin levels ever caused depression.
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By way of background; my son killed himself and another young man in 2009. He was prescribed an approved SSRI antidepressant 17 days beforehand. I absolutely believe that these ‘mind altering drugs’ are killing people at an alarming rate. Professor David Healy (a world leading expert on these drugs) has said that the pharmaceutical companies, in a court of law, have no choice but to admit that these drugs can cause suicide. According to Professor Healy, “there are 20 more Irish suicides per year than there would have been and 20 extra Irish cases of violence per year that can be linked back to antidepressants.” So given that the SSRI antidepressants have been on the market for 20 years; that’s 800 extra cases of suicide and violence caused by antidepressants in this country alone.
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The first major Case involving antidepressant induced suicide/homicide was in the US and involved a 60 year old man, Donald Schell. This man was put on Seroxat by his doctor, not for any mental illness, but for anxiety; yet 2 days later he shot and killed his wife, his daughter, his 9 month old granddaughter and then himself. The jury found that the drug had caused him to become suicidal and homicidal and found the pharmaceutical company liable, in that Case GlaxoSmithKline. There have been similar Cases since, the most recent in a Canadian trial where the Judge found that an antidepressant caused a 16 year old to kill his friend. The Judge (Justice Heinrichs) concluded that the teenager was no longer a danger and that at the time of the killing “his mental deterioration and resulting violence would not have taken place without exposure to Prozac.”Shane was sad, I know that; was that depression, no! Can these prescription drugs help with a broken heart or some other awful life experience? Can they un-break a heart or un-dead a loved one? No, but they can cause these terrible tragedies.
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From the time Shane was prescribed these drugs, he became very restless, which was very unlike him. He seemed to find it hard to stay in the one place for any length of time. What I didn’t understand until later was that this condition is called ‘akathisia’ and is known to be the precursor to suicide and/or homicide. Akathisia is an adverse effect which can be caused by these drugs and is described as ‘inner restlessness’. People suffering from this condition have described it as ‘a living hell’ and also that they would do anything to stop this feeling, including death as a welcome release. My son went from being well respected and loved by his lecturers, friends and family, to a person capable of destroying his own life and that of another human being in 17 days. Whether people believe me or not, matters little to me, as I cannot win either way. I can tell you this though: I knew my son inside out, and if it could happen to Shane, it could happen to you.
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The level of ‘antidepressant’ prescribing has never been so high and yet the suicide rate is rocketing. Join the dots here if you dare and please don’t argue the recession point; I’ve heard it already. We’ve come through the famine, oppressive English rule, Centuries of emigration and barefoot children; for goodness sake, get a grip! The suicide rate has never been so high and the barefoot children are long gone; presumably dead from old age and natural causes, not by their own hand. Each year there is (at least) one antidepressant prescription per year for every man, woman and child in Ireland. If these drugs actually cure people; how come we once had less than 1 per 1000 of us depressed, and now it’s more than 1 in 10? In the year 2010 the cost of medicines in the health service was €1.9 billion. Have we all gone mad? Why do we need €1.9 billion worth of medication every year; were we all born with inherent defects that only the (billion dollar) pharmaceutical industry can fix? Wake up and smell the pharma coffee when you take that statin this morning! Is that antidepressant you just consumed keeping you happy or can you remember either way? Without doubt the most medicated Country in the world is the US; would it surprise you to know that the life expectancy in the US has fallen below that of Cuba?

In the latest revelation within the mental health arena (Oct 2012), the British Medical Journal (BMJ) published a paper which showed that the risk of suicide (in the first year of treatment) for schizophrenia is extraordinarily high. For schizophrenia generally, you are 10 times more likely to be dead at the end of the first year of treatment than you were 100 years ago. Did you read that? 10 TIMES MORE THAN 100 YEARS AGO! Professor Healy (one of the authors) said “the actual risks of suicide (in the first year of treatment) were 100 times greater than those of the general population.”
Also this week, to much fanfare it has to be said, Minister Reilly said a “very good deal” was made with the Pharmaceutical Industry, to cut the State’s drugs bill by up to €400 million. This he said would benefit patients and the taxpayer. Right; excuse the cynicism here but that’s €400 million over 3 years, which is equivalent to a saving of €133 million a year. What’s €1.9 billion divided by €133 million? The Pharmaceutical industry may find this as amusing as I do; laughing all the way to the bank.

It amazes me that drugs with adverse effects such as suicide, depression, aggression and birth defects can be licenced by the Irish Medicines Board and yet the ‘free will’ of the pubic to medicate themselves is taken away by the banning of herbal remedies. I doubt if my son would be dead as a result of consuming a large dose of ‘Echinacea’. While I realise that all prescribed medications come with side-effects, we in Ireland are not afforded the same level of warning that other countries are. For example, all antidepressants come with a black-box warning in the US which signify that these drugs can have serious or even life-threatening adverse effects.
Of course herbal medicines are not without controversy either; St John’s wort, which has similar properties to an antidepressant, was widely known in the farming community to cause miscarriage and birth defects in cattle. Farmers took steps to prevent this drug from coming into contact with their animals; yet pregnant women are afforded no such warning. 1 in 10 pregnant Irish women are on antidepressants, leading to about 40 extra babies with significant birth defects and 200 extra miscarriages each year. So in the last 20 years, antidepressants have caused birth defects in 800 Irish babies and 4000 miscarriages.

I’m not entirely stupid; I know that some drugs can save lives and there will be people who say “the drugs have saved my life”. Who will speak for the dead people though, do they have a voice? €1.9 billion worth of drugs? Surely I’m not the only one who thinks that this is the biggest wheeze of the 21th Century. The number of people requiring medication is increasing every year. Will we eventually face a world where the majority of the human race will be ‘a bit mad ted’ and will therefore be the new class of norm? It could be seen as ‘the’ miracle of the 21th Century, where the meds are cast aside as the now normal ‘mad’ people don’t need them anymore; let’s all embrace the madness. It would surely be interesting to see what subsequently happens to the pharmaceutical industry; spontaneous combustion? Or just a frantic scrambling to find a way to convince people that medicating the ‘normal’ is actually now in Vogue? The old tale of ‘be careful what you wish for’ springs to mind. Dreadful weather, isn’t it?

The Irish Medicines Board declined to comment.
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Link to article. (Courtesy of Mike)
Newspaper and internet articles, Random

GlaxoSmithKline awarding the Irish media? No thanks!

‘RTE Radio 1’ has a Facebook page which proudly states “We’re delighted that RTÉ took home three awards at this year’s GSK Irish Medical Media Awards.” Two of the awards were won for documentaries, one on depression and another for clinical trials involving children.

Seriously though? That’s GSK; GlaxoSmithkline! Why is a pharmaceutical company (which has consistently been proven corrupt), sponsoring Ireland’s ‘Medical Media Awards’ and why is this acceptable?

Here’s an Irish article from 1998 which refers to Seroxat/Paxil called ‘Pill to melt shyness‘. The article states that people suffering from this ‘crippling’ illness ‘aren’t aware that they have such a condition’ and that ‘By itself, social phobia doesn’t bring on suicide but combined with other psychiatric illnesses victims are six times more likely than the general population to kill themselves‘. OK, so these poor unfortunate sufferers may go on to kill themselves from shyness and taking Seroxat should fix the problem? The article further states that the time this illness or ‘social phobia’ usually strikes is between the ages of 14 and 16 years old. Hang on a sec!! Panorama did a series of TV documentaries ‘outing’ GSK and the notorious Seroxat. They revealed, among lots of corrupt practices, that in one of GSK’s drug trials, adolescents were six times more likely to become suicidal after taking it. So the illness increases the risk of suicide by 6% and the cure by another 6%; a better mathematician than I would tell you, that’s not a good percentage for a so-called cure!

In July of this year GSK were fined $3 billion in the US for, among other things, illegally promoting this drug for children, despite being aware that the same drug could cause these children to kill themselves.

GSK’s ‘Better Together‘ campaign states…” to ensure Irish patients and consumers can get access to the health care they need, GSK recognise that we must work in partnership with Government, policy makers, healthcare professionals, patient and citizen groups.” I bet they do! Also this, “GSK wants to be healthcare partner of choice, valued for our expertise and trusted for our integrity.” What integrity is that exactly?

Ok, forgetting the fact that they have caused numerous ‘Seroxat induced’ deaths in children and adults; maybe it’s the ‘Avandia Scandal‘ integrity they’re talking about? Avandia is the drug that the FDA scientist ‘Dr. David Graham’ said ‘may have caused as many as 100,000 heart attacks, strokes, deaths and cases of heart failure’ before the drug was finally taken off the market. GSK still clung to the mantra the drug was safe though. Never admit anything? Surely GSK is the last company (apart from Lundbeck) that the Irish Medical Media should associate with? In my humble opinion, the medical media, whose job it is to investigate, should have done a little research into the company who was sponsoring these awards. Then they may have had some integrity of their own and told GSK to stick their awards where the sun doesn’t shine!

https://leoniefennell.wordpress.com/2012/07/04/irish-reports-on-gsks-fraudulent-marketing/

http://www.nytimes.com/2012/07/03/business/glaxosmithkline-agrees-to-pay-3-billion-in-fraud-settlement.html?pagewanted=all

http://fiddaman.blogspot.ie/2012/10/gsk-flying-flag-of-hypocrisy.html

Newspaper and internet articles, Random

Irish reports on GSK’s fraudulent marketing.

Following yesterdays news that GlaxoSmithKline (GSK) has been fined $3 billion for fraudulently marketing their products, I found the differences in Irish reporting and worldwide reports quite frightening. In the Irish Times and RTE News articles it reported, that among GlaxoSmithKline’s wrongdoing, was illegally marketing Paxil to children. OK SO FAR!

NO-WHERE in either Article does it say that the reason this marketing was so abhorrent, is because this drug increases the risk of suicide in children, a fact well known to GSK and the regulators (Under 25’s).

In contrast to the Irish reports, the New York Times and The UK Independent both include the fact that this drug can cause suicide in young people. I wonder why Irish people are not getting the same facts.

The other surprise was that no-where in these Irish Articles did it say that Paxil is marketed as Seroxat in Ireland. The Irish public would probably have never heard of Paxil but would certainly have heard of the publicity, mostly bad, surrounding Seroxat.

I recommend, that if anyone really wants to know the true appalling facts surrounding GSK, then there is no better place to get information than Bobby and Truthman’s websites.

Irish reporting: Irish Times Article and The RTE News Article.

UK and US reporting: UK Independent Article and The New York Times Article.

Interestingly Seroxat was again in the Irish papers (Irish Independent) this week, named as Seroxat not Paxil, here “Man attacked terrified party guest with sword after mixing alcohol and medication”.

Update: What I should have made clearer is that the European suicide warnings with these drugs are for under 25’s. If anyone has read the stories on this blog and others, age has nothing to do with a drug-induced suicide. Ask Brian PalmerRobert Raines or Donald Schell (Prozac, Celexa and Seroxat/Paxil)

Cases, cipramil (celexa) stories,

R v Smallshire…influenced by Citalopram!

R v Smallshire [2008] All ER (D) 186 (Dec)

This is an English Appeal Case appealing the Length of sentence imposed upon the defendant (Ronald Smallshire).

The background to the Case…

The victim, 23, and his three step-sisters were walking their two dogs. One of the dogs attacked the defendant, his wife and one of the defendant’s dogs. The defendant, Mr Smallshire, 56, who had consumed alcohol, went into his house, got a steak knife and emerged wearing a coat with the hood pulled over his head. He hit the victim to the head and back, causing him to fall to the ground. Mr Smallshire then straddled the victim and stabbed him 19 times, also to the head and back. The victim suffered a pneumothorax (collapsed lung) and stab wounds. He stayed in hospital overnight. He made a good recovery but he and his stepsisters suffered psychological effects.

The Defendant Mr Smallshire had no previous convictions and was described by the Court as ‘a man of impeccably good character’. The Court further stated that it was quite apparent that his conduct was out of character. So what could make a person behave in such an uncharacteristic fashion? Ah yes, Citalopram again!

The appeal centered around the side-effects of the medication he was prescribed. 11 days before the incident, Mr Smallshire was prescribed Citalopram. Mr Smallshire said, upon starting the medication, he felt agitated, unreal and confused.

Excerpt;

Mr Smallshire relies, in support of his challenge to conviction, upon evidence of Dr Andrew Herxheimer, a consultant clinical pharmacologist, experienced in the investigation and evaluation of the adverse effects of drug therapy and who in recent years has studied a large number of reports of effects relating to SSRI (Select Seroxat Inhibitors) antidepressant drugs, of which Citalopram is one.

Dr Herxheimer wrote a report for the Court where he concluded:

“. . . citalopram very likely contributed decisively to Mr Smallshire’s actions on 16 December 2005. He had started taking this antidepressant medication 11 days earlier; its concentration in his brain would have been steadily increasing from about seven days. It is highly probable that alcohol augmented the effect of the drug: on its own alcohol would not account for his behaviour.”

In allowing the appeal, the Court reduced Mr Smallshire’s sentence from six-and-a-half years to four-and-a-half years.  Full Judgment R v Smallshire

cipramil (celexa) stories,, lundbeck, Newspaper and internet articles

Are antidepressants the cause of the recent spate of murder/suicides in China? 抗抑鬱藥,最近接連發生在中國的謀殺 /自殺的原因?

抗抑鬱藥,最近接連發生在中國的謀殺 /自殺的原因?

Are antidepressants the cause of the latest spate of murder/suicides in China?

In the last year there has been a series of newspaper articles concerning recent murder/suicides in China. It seems that this kind of tragedy was virtually unheard of in China until recently. China is relatively new to the antidepressant market, I wouldn’t be too sure that the Chinese are aware of the dangers; I’m sure the various drug companies are not volunteering the information that these drugs can actually cause both suicide and homicide.

As you my be aware, my son killed himself and another young man in Aug 2009. I have the expert report which Professor Healy did for Shane’s Inquest, stating that, in his opinion, this was caused by Cipramil. For anyone that wants to read his report, I have blanked out the names of the other people involved but will attach it here…Professor Healy’s Report March 2010.

Back to China…

School attacks in the People’s Republic of ChinaWikipedia

A series of uncoordinated mass stabbings, hammer attacks, and cleaver attacks in the People’s Republic of China began in March 2010. The spate of attacks left at least 21 dead and some 90 injured.

Kindergarten killings are a turning point for ChinaThe Telegraph

The series of kindergarten murders that has swept across China marks a turning point for Chinese society.

In a country which reveres children – especially since the one-child policy was introduced in the late 1970s – it is difficult to imagine how any atrocity could be worse than the premeditated murder of innocent toddlers. Since March 23, when a mentally-unstable doctor stabbed eight primary school children to death, each copycat attack has added to parents’ fears.

Life on the margins of Chinese society has always been unfair and difficult, but it is near impossible to imagine the rage that must have driven these men to slit the throats of young children. Clearly, something is very rotten in China.

Exactly what is going on in China?? The Moderator

Exactly what is going on in China?

A rash of bloody, knife and meat cleaver murders of small school kids by adults have stunned China, a country where children are treasured. It seemingly matches the inexpicable killing sprees that peppered American history over the past few decades. The question is “why.” And the answer so far is: “no one knows” — but a lot of parents now fear.

……………………..

The most widely-used antidepressants in China by the end of last year were GlaxoSmithKline’s Paxil/Seroxat (paroxetine) with a value market share of 18%, followed by Pfizer’s Zoloft (sertraline; 10%) and Eli Lilly’s Prozac (fluoxetine; also 10%). Lundbeck’s older drug Cipramil (citalopram), also sold by Xian-Janssen, and Lexapro had market shares of 6.5% and 3.0% respectively.

Soo,  the Chinese people have been introduced to Seroxat, Prozac, Zoloft, Cipramil and Lexapro which can cause suicide and homicide ideation and there has been a spate of murder/suicides. Now isn’t that a co-incidence.

Has it anything to do with Lundbeck’s recent marketing push on Lexapro in China?

Lundbeck to establish a strong, dedicated sales… FE Investegate

Lundbeck will substantially increase sales and marketing efforts behind Lexapro in China. Lundbeck already has a foothold in China and stands to benefit from the rapidly evolving Chinese CNS market.

Lundbeck sees China as land of opportunity for Lexapro…PharmaTimesOnline

Lundbeck has unveiled plans to double its sales force in China with a specific emphasis on promoting the blockbuster Lexapro in the growing antidepressant market there.

So it begs the question, considering all of the above drugs can cause suicide and homicide, how many of the perpetrators were on an antidepressant?

One worrying aspect is that Lundbeck have just launched Lexapro in Japan. So it remains to be seen if the next headlines will be “School attacks in Japan” and “Exactly what is going on in Japan”?

GSK have already trialed the notorious Seroxat on Japanese  7-17 year olds, despite the fact that ssri’s have been proven to be detrimental to children, even causing deaths. But then, what do you expect from a company with such dubious ethics (on an equal par with Lundbeck) who see no moral issue with doing drug trials on children as young as 7?  Link.